Anti-BMP5 antibody (114-163 aa) (STJ91866) STJ91866 上海玉博生物科技有限公司

Anti-BMP5 antibody (114-163 aa) (STJ91866)

简单介绍

Anti-BMP5 antibody (114-163 aa) (STJ91866)

产品描述

Host:	Rabbit
Applications:	WB/IHC/IF/ELISA
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Bone morphogenetic protein 5 (114-163 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:40000 IF 1:50-200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	BMP5
Gene ID:	653
Uniprot ID:	BMP5_HUMAN
Immunogen Region:	114-163 aa
Specificity:	BMP-5 Polyclonal Antibody detects endogenous levels of BMP-5 protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human BMP-5 at the amino acid range 114-163

Function	Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including cartilage and bone formation or neurogenesis. Initiates the canonical BMP signaling cascade by associating with type I receptor BMPR1A and type II receptor BMPR2. In turn, BMPR1A propagates signal by phosphorylating SMAD1/5/8 that travel to the nucleus and act as activators and repressors of transcription of target genes. Can also signal through non-canonical pathway such as MAPK p38 signaling cascade to promote chondrogenic differentiation. Promotes the expression of HAMP, this is repressed by its interaction with ERFE.
Protein Name	Bone Morphogenetic Protein 5 Bmp-5
Cellular Localisation	Secreted
Alternative Antibody Names	Anti-Bone Morphogenetic Protein 5 antibody Anti-Bmp-5 antibody Anti-BMP5 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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