Anti-CD35/CR1 antibody [E11] {APC} (STJA0001482) STJA0001482 上海玉博生物科技有限公司

Anti-CD35/CR1 antibody [E11] {APC} (STJA0001482)

简单介绍

Anti-CD35/CR1 antibody [E11] {APC} (STJA0001482)

产品描述

Host:	Mouse
Applications:	FC
Reactivity:	Human
Note:	FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description:	Mouse monoclonal antibody anti-Complement receptor type 1 is suitable for use in Flow Cytometry research applications.

Clonality:	Monoclonal
Clone ID:	E11
Conjugation:	APC
Isotype:	IgG1k
Formulation:	PBS with 0.05% Proclin300, 1% BSA
Storage Instruction:	Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product.

Tissue Specificity	Present on erythrocytes, a subset of T cells, mature B cells, follicular dendritic cells, monocytes and granulocytes.
Function	Membrane immune adherence receptor that plays a critical role in the capture and clearance of complement-opsonized pathogens by erythrocytes and monocytes/macrophages. Mediates the binding by these cells of particles and immune complexes that have activated complement to eliminate them from the circulation. Acts also in the inhibition of spontaneous complement activation by impairing the formation and function of the alternative and classical pathway C3/C5 convertases, and by serving as a cofactor for the cleavage by factor I of C3b to iC3b, C3c and C3d,g, and of C4b to C4c and C4d. Also plays a role in immune regulation by contributing, upon ligand binding, to the generation of regulatory T cells from activated helper T cells. (Microbial infection) Acts as a receptor for Epstein-Barr virus.
Protein Name	Complement Receptor Type 1 C3b/C4b Receptor Cd Antigen Cd35
Database Links	Reactome: R-HSA-6798695 Reactome: R-HSA-8877330 Reactome: R-HSA-977606
Cellular Localisation	Membrane Single-Pass Type I Membrane Protein
Alternative Antibody Names	Anti-Complement Receptor Type 1 antibody Anti-C3b/C4b Receptor antibody Anti-Cd Antigen Cd35 antibody Anti-CR1 antibody Anti-C3BR antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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