您好,欢迎来到仪表展览网!
请登录
免费注册
分享
微信
新浪微博
人人网
QQ空间
开心网
豆瓣
会员服务
进取版
标准版
尊贵版
|
设为首页
|
收藏
|
导航
|
帮助
|
移动端
|
官方微信扫一扫
微信扫一扫
收获行业前沿信息
产品
资讯
请输入产品名称
噪声分析仪
纺织检测仪器
Toc分析仪
PT-303红外测温仪
转矩测试仪
继电保护试验仪
定氮仪
首页
产品
知识
专题
词条
品牌
资料
展会
成功案例
网上展会
词多 效果好 就选易搜宝!
上海玉博生物科技有限公司
新增产品
|
公司简介
注册时间:
2014-10-23
联系人:
电话:
Email:
首页
公司简介
产品目录
公司新闻
技术文章
资料下载
成功案例
人才招聘
荣誉证书
联系我们
产品目录
A类
absolute antibody
a
a & g pharmaceuticals官网
a.g scientific
Aalto
Aalto Scientific
aaltobioreagents
aaltoscientific
aat
aat bioquest
B类
Bacharach Inc
Bachem
backman coulter
badrilla
Bangs
bangs laboratories
bangslab
bangslabs
Barnant Company
Barnstead International
C类
CASMASCI
C
Cadence Science
caisson labs
Calbiochem
CalBioreagents
calbiotech
California Bioscience
california bioscience2
california peptide research
D类
Dade-Behring
daiichi fine chemical
Dako
Davis Instruments
DB Biotech
dbbiotech
DBS
DCS
De Novo Software
deciphergen
E类
EpiCypher
eagle
Eagle BioSciences
Eagle Manufacturing
Eagle Manufacturing Company
Eagle Manufacturing Company/Eagle Mfg. Company
Eagle Thermoplastics Inc.
EarthOx
eastcoast
Eastwood Manufacturing Co.
F类
FabGennix
Falcon Safety
Falcon Safety Products Inc.
Fawcett Company Inc.
FD NEURO TECHNOLOGIES
FD NeuroTechnologies
fd neurotechnologies2
FDNeuroo
fdneurotech
fdneurotech/fd neurotechnologies/FD NEURO TECHNOLOGIES
G类
G C Fuller
GALAB technologies
gallusimmunotech
Gast Manufacturing, Inc.
Gawet Marble
GBD
gbi
gbi-inc
gbiosciences
GBP
H类
Haematologic Technologies
Haematologic Technologies Inc
hamilton
Hampton
Handyem
HANNA
hawksley
HBM
HBT
Hellma
I类
Isosep
IBA
IBA-go
ibexpharma
Ibidi
IBL
IBL-America
ibtsystems
ICLLab
Icosagen
J类
Jackson
Jackson ImmunoResearch
JCRB
jena bioscience
jenabioscience
JPC
JRS Medical
K类
Kalen Biomedical
Kamiya
kapabiosystems
katchem
katena
kentscientific
kerafast
KERRY
Kingfisher Biotech
Kollodis BioSciences
L类
Labfrontier
Labnet
labscientific
Labvision
Lancaster
larodan
LaysanBio
LC Laboratories
lclabs
LDN
M类
moradec
molzym
magsphere
Mabtech
Macherey-Nagel
macrocyclics
Macs Miltenyi
Magen
MagnaMedics
maravai lifesciences
N类
nanocomposix
Nexcelom Bioscience
nabertherm
Nalgene
Nano
NanoBac
NanoLight Technologies
nanoprobes
nanoscience
NANOSOFT POLYMERS
O类
Ocean NanoTech
OEM Concept
OET
ohaus
ohio valley specialty
oligoengine
Omega试剂盒
omicron Biochemicals
omicronbio
Omni International
P类
panagene
Polymer source
phosphorex
Pall
PANATecs
Panomics
panpath
Parafilm
PBL InterferonSource
Pel-Freez
Q类
QAbio
QBG
QED bioscience
QEDbioscience
Qiagen
Quansys Biosciences
Quanta Biosciences
quantabiodesign
quickzyme
Quidel
R类
rossix
R&D
Rainin
RayBiotech
RB
RBC bioscience
R-biopharm
RECI
Relia Tech
RELIATech
S类
Spirochrome
S&S
SABiosciences
salimetrics
Sanquin
Santa Cruz
sanyo
Sartorius
SBA
SBI
T类
terrace biotech
taiclone
Takara
TaqMan
targetingsystems
TCI
Techne
Technoclone
Tecrea
Ted Pella
U类
UBPBIO
U-Cytech
UmanDiagnostics
UnionBiometrica
unitedchem
Upstate
Us biological
Usb
usbio
Usbiological
V类
valasciences
Valley Biomedical
Varian
Vector
Vector Laboratories
Vectorlabs
verichem
veridex
viagenbiotech
ViennaLab
W类
Wako
warner
waters
werner bioAgents
whatman
WHO
Wieslab
worthington
wpiinc
WSU Monoclonal Antibody Center
X类
Xcessbio
X-Rite
Y类
Yakult
yesbiotech
YSL
Z类
zedira
ZENOAQ
ZeptoMetrix
zyagen
zyagen Laboratories
Zymed
Zymo Research
zytovision
5 prime
3-M Company
3hbiomedical
3h biomedical
3dhistech
3D Matrix
3D Biomatrix
胎牛血清
85ml离心管
密理博
5prime
4adi
4rtilab
实验仪器
实验试剂
细胞分离液
培养基
转染试剂
外泌体提取试剂盒
硫酸钠葡聚糖
胶原酶
实验耗材
封板膜
细胞计数板
测试
当前位置:
首页
>>>
产品目录
>>>
S类
>>> 
ST john's laboratory
仪表展览网
>>>
展馆展区
>>>
Anti-CD36 antibody [FA6-152] (STJ16100295)
>
Anti-CD36 antibody [FA6-152] (STJ16100295)
产品资料
Anti-CD36 antibody [FA6-152] (STJ16100295)
如果您对该产品感兴趣的话,可以
产品名称:
Anti-CD36 antibody [FA6-152] (STJ16100295)
产品型号:
STJ16100295-1
产品展商:
ST john's laboratory
产品文档:
无相关文档
简单介绍
Anti-CD36 antibody [FA6-152] (STJ16100295)
产品描述
Host:
Mouse
Applications:
IHC-F/FC/ELISA/IF/IP
Reactivity:
Human
Note:
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:
Mouse monoclonal antibody anti-CD36 is suitable for use in Immunohistochemistry, Flow Cytometry, ELISA, Immunofluorescence and Immunoprecipitation research applications.
Clonality:
Monoclonal
Clone ID:
FA6-152
Conjugation:
Unconjugated
Isotype:
IgG1
Formulation:
PBS with 0.1% BSA and 0.02% sodium azide
Concentration:
100 ug/mL
Storage Instruction:
Store at 2-8°C upon receipt.
Gene Symbol:
CD36
Gene ID:
948
Uniprot ID:
CD36_HUMAN
Post Translational Modifications
N-glycosylated and O-glycosylated with a ratio of 2:1. Palmitoylated by ZDHHC5. Palmitoylation is required for proper localization at the plasma membrane. Ubiquitinated at Lys-469 and Lys-472. Ubiquitination is induced by fatty acids such as oleic acid and leads to degradation by the proteasome. Ubiquitination and degradation are inhibited by insulin which blocks the effect of fatty acids.
Function
Multifunctional glycoprotein that acts as receptor for a broad range of ligands. Ligands can be of proteinaceous nature like thrombospondin, fibronectin, collagen or amyloid-beta as well as of lipidic nature such as oxidized low-density lipoprotein (oxLDL), anionic phospholipids, long-chain fatty acids and bacterial diacylated lipopeptides. They are generally multivalent and can therefore engage multiple receptors simultaneously, the resulting formation of CD36 clusters initiates signal transduction and internalization of receptor-ligand complexes. The dependency on coreceptor signaling is strongly ligand specific. Cellular responses to these ligands are involved in angiogenesis, inflammatory response, fatty acid metabolism, taste and dietary fat processing in the intestine (Probable). Binds long-chain fatty acids and facilitates their transport into cells, thus participating in muscle lipid utilization, adipose energy storage, and gut fat absorption. Mechanistically, binding of fatty acids activates downstream kinase LYN, which phosphorylates the palmitoyltransferase ZDHHC5 and inactivates it, resulting in the subsequent depalmitoylation of CD36 and caveolar endocytosis. In the small intestine, plays a role in proximal absorption of dietary fatty acid and cholesterol for optimal chylomicron formation, possibly through the activation of MAPK1/3 (ERK1/2) signaling pathway. Involved in oral fat perception and preferences. Detection into the tongue of long-chain fatty acids leads to a rapid and sustained rise in flux and protein content of pancreatobiliary secretions. In taste receptor cells, mediates the induction of an increase in intracellular calcium levels by long-chain fatty acids, leading to the activation of the gustatory neurons in the nucleus of the solitary tract. Important factor in both ventromedial hypothalamus neuronal sensing of long-chain fatty acid and the regulation of energy and glucose homeostasis. Receptor for thrombospondins, THBS1 and THBS2, mediating their antiangiogenic effects. Involved in inducing apoptosis in podocytes in response to elevated free fatty acids, acting together with THBS1. As a coreceptor for TLR4:TLR6 heterodimer, promotes inflammation in monocytes/macrophages. Upon ligand binding, such as oxLDL or amyloid-beta 42, interacts with the heterodimer TLR4:TLR6, the complex is internalized and triggers inflammatory response, leading to NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion, through the priming and activation of the NLRP3 inflammasome. Selective and nonredundant sensor of microbial diacylated lipopeptide that signal via TLR2:TLR6 heterodimer, this cluster triggers signaling from the cell surface, leading to the NF-kappa-B-dependent production of TNF, via MYD88 signaling pathway and subsequently is targeted to the Golgi in a lipid-raft dependent pathway. (Microbial infection) Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and the internalization of particles independently of TLR signaling.
Protein Name
Platelet Glycoprotein 4
Fatty Acid Translocase
Fat
Glycoprotein Iiib
Gpiiib
Leukocyte Differentiation Antigen Cd36
Pas Iv
Pas-4
Platelet Collagen Receptor
Platelet Glycoprotein Iv
Gpiv
Thrombospondin Receptor
Cd Antigen Cd36
Database Links
Reactome: R-HSA-114608
Reactome: R-HSA-1236973
Reactome: R-HSA-1236974
Reactome: R-HSA-166058
Reactome: R-HSA-168188
Reactome: R-HSA-1989781
Reactome: R-HSA-3000471
Reactome: R-HSA-381340
Reactome: R-HSA-434313
Reactome: R-HSA-5602498
Reactome: R-HSA-5603041
Reactome: R-HSA-5686938
Reactome: R-HSA-6785807
Reactome: R-HSA-6798695
Cellular Localisation
Cell Membrane
Multi-Pass Membrane Protein
Membrane Raft
Golgi Apparatus
Apical Cell Membrane
Upon Ligand-Binding
Internalized Through Dynamin-Dependent Endocytosis
Alternative Antibody Names
Anti-Platelet Glycoprotein 4 antibody
Anti-Fatty Acid Translocase antibody
Anti-Fat antibody
Anti-Glycoprotein Iiib antibody
Anti-Gpiiib antibody
Anti-Leukocyte Differentiation Antigen Cd36 antibody
Anti-Pas Iv antibody
Anti-Pas-4 antibody
Anti-Platelet Collagen Receptor antibody
Anti-Platelet Glycoprotein Iv antibody
Anti-Gpiv antibody
Anti-Thrombospondin Receptor antibody
Anti-Cd Antigen Cd36 antibody
Anti-CD36 antibody
Anti-GP3B antibody
Anti-GP4 antibody
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
产品留言
标题
联系人
联系电话
内容
验证码
点击换一张
注:1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!
温馨提示:为规避购买风险,建议您在购买前务必确认供应商资质与产品质量。
免责申明:以上内容为注册会员自行发布,若信息的真实性、合法性存在争议,平台将会监督协助处理,
欢迎举报
产品留言
标题
内容
联系人
联系电话
电子邮件
公司名称
联系地址
验证码
点击换一张
注:1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!
相关产品
Anti-Pan myristoylation antibody STJ98665
ST john's laboratory中国代理商2020
Anti-14-3-3 beta/Theta antibody (1-100) [S1MR] (STJ11103651) STJ11103651
Anti-14-3-3 Beta/Zeta antibody (151-200 aa) (STJ91368) STJ91368
Anti-14-3-3 sigma/Stratifin antibody (Internal) (STJ70838) STJ70838-100
Anti-14-3-3 sigma/Stratifin, Biotinylated antibody (Internal) {Biotin} (STJ73293) STJ73293-100
Anti-14-3-3 tau/YWHAQ antibody (Internal) (STJ71355) STJ71355-100
Anti-2 NA-O-methyl-2mA antibody (STJ11100889) STJ11100889
Anti-2 NA-O-methylcytidine/Cm antibody (STJ11103959) STJ11103959
Anti-2 NA-O-methylcytidine/Cm antibody [S4061RM] (STJ11104061) STJ11104061
Anti-2019-covid N protein antibody (STJA0010175) STJA0010175
Anti-2019-covid N protein antibody (STJA0010176) STJA0010176
Anti-2019-nCoV antibody [S0MR] (STJ11101210) STJ11101210
Anti-2019-nCoV antibody [S1MR] (STJ11101211) STJ11101211
Anti-25-OH-VD antibody [S5669RM] (STJ11105669) STJ11105669
若网站内容侵犯到您的权益,请通过网站上的联系方式及时联系我们修改或删除
沪公网安备 31011002002624号