Anti-CD3EAP antibody (1-170) (STJ118539) STJ118539 上海玉博生物科技有限公司

Anti-CD3EAP antibody (1-170) (STJ118539)

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产品名称：Anti-CD3EAP antibody (1-170) (STJ118539)
产品型号：STJ118539
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-CD3EAP antibody (1-170) (STJ118539)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CD3EAP (1-170) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	POLR1G
Gene ID:	10849
Uniprot ID:	RPA34_HUMAN
Immunogen Region:	1-170
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human CD3EAP (NP_036231.1).
Immunogen Sequence:	MEEPQAGDAARFSCPPNFTA KPPASESPRFSLEALTGPDT ELWLIQAPADFAPECFNGRH VPLSGSQIVKGKLAGKRHRY RVLSSCPQAGEATLLAPSTE AGGGLTCASAPQGTLRILEG PQQSLSGSPLQPIPASPPPQ IPPGLRPRFCAFGGNPPVTG PRSALAPNLL

Post Translational Modifications	Isoform 2 undergoes tyrosine phosphorylation upon T-cell receptor (TCR) stimulation. This phosphorylation has not been confirmed by other groups. Isoform 1 is phosphorylated on tyrosine residues in initiation-competent Pol I-beta complexes but not in Pol I-alpha complexes.
Function	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Isoform 1 is involved in UBTF-activated transcription, presumably at a step following PIC formation. Isoform 2 has been described as a component of preformed T-cell receptor (TCR) complex.
Protein Name	Dna-Directed Rna Polymerase I Subunit Rpa34 A34.5 Antisense To Ercc-1 Protein Ase-1 Cd3-Epsilon-Associated Protein Cd3e-Associated Protein Dna-Directed Rna Polymerase I Subunit G Rna Polymerase I-Associated Factor Paf49
Database Links	Reactome: R-HSA-427413 Reactome: R-HSA-5250924 Reactome: R-HSA-73762 Reactome: R-HSA-73772 Reactome: R-HSA-73863
Cellular Localisation	Nucleus Nucleolus Chromosome Found At The Fibrillar Centers Of The Nucleolus In Interphase And During Cell Division It Is Localized To The Nucleolus Organizer Regions Of The Chromosomes
Alternative Antibody Names	Anti-Dna-Directed Rna Polymerase I Subunit Rpa34 antibody Anti-A34.5 antibody Anti-Antisense To Ercc-1 Protein antibody Anti-Ase-1 antibody Anti-Cd3-Epsilon-Associated Protein antibody Anti-Cd3e-Associated Protein antibody Anti-Dna-Directed Rna Polymerase I Subunit G antibody Anti-Rna Polymerase I-Associated Factor Paf49 antibody Anti-POLR1G antibody Anti-ASE1 antibody Anti-CAST antibody Anti-CD3EAP antibody Anti-PAF49 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-CD3EAP antibody (1-170) (STJ118539)