Anti-BS69/ZMYND11 antibody (N-Term) (STJ70304) STJ70304-100 上海玉博生物科技有限公司

Anti-BS69/ZMYND11 antibody (N-Term) (STJ70304)

简单介绍

Anti-BS69/ZMYND11 antibody (N-Term) (STJ70304)

产品描述

Host:	Goat
Applications:	Pep-ELISA/IF
Reactivity:	Human/Mouse/Rat/Dog/Pig/Cow
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Goat polyclonal antibody anti-BS69/ZMYND11 (N-Term) is suitable for use in ELISA and Immunofluorescence research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	0.5 mg/mL
Dilution Range:	IF-Strong expression of the protein seen in the nuclei of U2OS cells. 10µg/ml ELISA-antibody detection limit dilution 1:32000.
Storage Instruction:	Store at-20°C on receipt and minimise freeze-thaw cycles.

Gene Symbol:	ZMYND11
Gene ID:	10771
Uniprot ID:	ZMY11_HUMAN
Immunogen Region:	N-Term
Accession Number:	NP_006615.2; NP_997644.2; NP_001189393.1; NP_001189394.1; NP_001189395.1; NP_001189396.1; NP_001189397.1
Specificity:	This antibody is expected to recognise all reported human isoforms (NP_006615.2; NP_997644.2; NP_001189393.1; NP_001189394.1; NP_001189395.1; NP_001189396.1; NP_001189397.1).
Immunogen Sequence:	SRVHGMHPKETT

Post Translational Modifications	Sumoylated following its interaction with PIAS1 and UBE2I. Ubiquitinated, leading to proteasomal degradation.
Function	Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Binds non-specifically to dsDNA. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth. (Microbial infection) Inhibits Epstein-Barr virus EBNA2-mediated transcriptional activation and host cell proliferation, through direct interaction.
Protein Name	Zinc Finger Mynd Domain-Containing Protein 11 Adenovirus 5 E1a-Binding Protein Bone Morphogenetic Protein Receptor-Associated Molecule 1 Protein Bs69
Cellular Localisation	Nucleus Chromosome Associates With Chromatin And Mitotic Chromosomes
Alternative Antibody Names	Anti-Zinc Finger Mynd Domain-Containing Protein 11 antibody Anti-Adenovirus 5 E1a-Binding Protein antibody Anti-Bone Morphogenetic Protein Receptor-Associated Molecule 1 antibody Anti-Protein Bs69 antibody Anti-ZMYND11 antibody Anti-BRAM1 antibody Anti-BS69 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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