Anti-BSCL2 antibody (265-363) (STJ116793) STJ116793 上海玉博生物科技有限公司

Anti-BSCL2 antibody (265-363) (STJ116793)

简单介绍

Anti-BSCL2 antibody (265-363) (STJ116793)

产品描述

Host:	Rabbit
Applications:	WB/IHC/IF
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-BSCL2 (265-363) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:1000 IHC-P 1:50-1:200 IF/ICC 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	BSCL2
Gene ID:	26580
Uniprot ID:	BSCL2_HUMAN
Immunogen Region:	265-363
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 265-363 of human BSCL2 (NP_116056.3).
Immunogen Sequence:	RHRFSLQVNIRKRDNSRKEV QRRISAHQPGPEGQEESTPQ SDVTEDGESPEDPSGTEGQL SEEEKPDQQPLSGEEELEPE ASDGSGSWEDAALLTEANL

Tissue Specificity	Expressed in motor neurons in the spinal cord and cortical neurons in the frontal lobe (at protein level). Highly expressed in brain, testis and adipose tissue.
Function	Plays a crucial role in the formation of lipid droplets (LDs) which are storage organelles at the center of lipid and energy homeostasis. In association with LDAF1, defines the sites of LD formation in the ER. Also required for growth and maturation of small nascent LDs into larger mature LDs. Mediates the formation and/or stabilization of endoplasmic reticulum-lipid droplets (ER-LD) contacts, facilitating protein and lipid delivery from the ER into growing LDs. Regulates the maturation of ZFYVE1-positive nascent LDs and the function of the RAB18-ZFYVE1 complex in mediating the formation of ER-LD contacts. Binds anionic phospholipids including phosphatidic acid. Plays an important role in the differentiation and development of adipocytes.
Protein Name	Seipin Bernardinelli-Seip Congenital Lipodystrophy Type 2 Protein
Cellular Localisation	Endoplasmic Reticulum Membrane Multi-Pass Membrane Protein Lipid Droplet Localizes At Endoplasmic Reticulum-Lipid Droplets (Er-Ld) Contact Sites
Alternative Antibody Names	Anti-Seipin antibody Anti-Bernardinelli-Seip Congenital Lipodystrophy Type 2 Protein antibody Anti-BSCL2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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