Human PCGF4 (Polycomb Group Ring Finger Protein 4) Sandwich ELISA Kit (STJE0011301) STJE0011301 上海玉博生物科技有限公司

Human PCGF4 (Polycomb Group Ring Finger Protein 4) Sandwich ELISA Kit (STJE0011301)

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产品名称：Human PCGF4 (Polycomb Group Ring Finger Protein 4) Sandwich ELISA Kit (STJE0011301)
产品型号：STJE0011301
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human PCGF4 (Polycomb Group Ring Finger Protein 4) Sandwich ELISA Kit (STJE0011301)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.122ng/mL
Detection Limit:	0.312-20ng/mL
Short Description:	This PCGF4 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	BMI1
Gene ID:	100532731/648
Uniprot ID:	BMI1_HUMAN
Sample Type:	tissue homogenates or other biological fluids.

Tissue Specificity
Post Translational Modifications	Monoubiquitinated. May be polyubiquitinated.which does not lead to proteasomal degradation.
Function	Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones.it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. The complex composed of RNF2, UB2D3 and BMI1 binds nucleosomes, and has activity only with nucleosomal histone H2A. In the PRC1-like complex, regulates the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Protein Name	Polycomb Complex Protein Bmi-1 Polycomb Group Ring Finger Protein 4 Ring Finger Protein 51
Database Links	Reactome: R-HSA-2559580 Reactome: R-HSA-3108214 Reactome: R-HSA-3899300 Reactome: R-HSA-4551638 Reactome: R-HSA-4570464 Reactome: R-HSA-4655427 Reactome: R-HSA-8939243 Reactome: R-HSA-8943724 Reactome: R-HSA-8953750
Cellular Localisation	Nucleus Cytoplasm
Alternative ELISA Names	Polycomb Complex Protein Bmi-1 ELISA kit Polycomb Group Ring Finger Protein 4 ELISA kit Ring Finger Protein 51 ELISA kit BMI1 ELISA kit PCGF4 ELISA kit RNF51 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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