Human PLIN5 (Perilipin 5) Sandwich ELISA Kit Ready-To-Use (STJE0017941) STJE0017941 上海玉博生物科技有限公司

Human PLIN5 (Perilipin 5) Sandwich ELISA Kit Ready-To-Use (STJE0017941)

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产品名称：Human PLIN5 (Perilipin 5) Sandwich ELISA Kit Ready-To-Use (STJE0017941)
产品型号：STJE0017941
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human PLIN5 (Perilipin 5) Sandwich ELISA Kit Ready-To-Use (STJE0017941)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.065ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This PLIN5 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	PLIN5
Gene ID:	440503
Uniprot ID:	PLIN5_HUMAN
Immunogen Region:	Ready-To-Use
Sample Type:	tissue homogenates, cell lysates or other biological fluids.

Tissue Specificity	Expressed in skeletal muscle, liver, heart and kidney.
Post Translational Modifications	Phosphorylated by PKA. Phosphorylated on serine in skeletal muscle at rest or upon lipolytic stimulation.
Function	Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues. Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation. In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE. Reduces the triacylglycerol hydrolase activity of PNPLA2 by recruiting and sequestering PNPLA2 to lipid droplets. Phosphorylation by PKA enables lipolysis probably by promoting release of ABHD5 from the perilipin scaffold and by facilitating interaction of ABHD5 with PNPLA2. Also increases lipolysis through interaction with LIPE and upon PKA-mediated phosphorylation of LIPE.
Protein Name	Perilipin-5 Lipid Storage Droplet Protein 5
Database Links
Cellular Localisation	Lipid Droplet Cytoplasm Mitochondrion Lipid Droplet Surface-Associated Exchanges Between Lipid Droplets And The Cytoplasm
Alternative ELISA Names	Perilipin-5 ELISA kit Lipid Storage Droplet Protein 5 ELISA kit PLIN5 ELISA kit LSDP5 ELISA kit OXPAT ELISA kit PAT-1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Human PLIN5 (Perilipin 5) Sandwich ELISA Kit Ready-To-Use (STJE0017941)