Anti-CDC16 antibody (371-620) (STJ29277) STJ29277 上海玉博生物科技有限公司

Anti-CDC16 antibody (371-620) (STJ29277)

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产品名称：Anti-CDC16 antibody (371-620) (STJ29277)
产品型号：STJ29277
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-CDC16 antibody (371-620) (STJ29277)

产品描述

Host:	Rabbit
Applications:	WB/IHC
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CDC16 (371-620) is suitable for use in Western Blot and Immunohistochemistry research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000 IHC-P 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CDC16
Gene ID:	8881
Uniprot ID:	CDC16_HUMAN
Immunogen Region:	371-620
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 371-620 of human CDC16 (NP_003894.3).
Immunogen Sequence:	MLYIGLEYGLTNNSKLAERF FSQALSIAPEDPFVMHEVGV VAFQNGEWKTAEKWFLDALE KIKAIGNEVTVDKWEPLLNN LGHVCRKLKKYAEALDYHRQ ALVLIPQNASTYSAIGYIHS LMGNFENAVDYFHTALGLRR DDTFSVTMLGHCIEMYIGDS EAYIGADIKDKLKCYDFDVH TMKTLKNIISPPWDFREFEV EKQTAEETGLTPLETSRKTP DSRPSLEETFEIEMNESDM

Post Translational Modifications	Phosphorylated. Phosphorylation on Ser-560 occurs specifically during mitosis.
Function	Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Protein Name	Cell Division Cycle Protein 16 Homolog Anaphase-Promoting Complex Subunit 6 Apc6 Cdc16 Homolog Cdc16hs Cyclosome Subunit 6
Database Links	Reactome: R-HSA-141430 Reactome: R-HSA-174048 Reactome: R-HSA-174084 Reactome: R-HSA-174154 Reactome: R-HSA-174178 Reactome: R-HSA-174184 Reactome: R-HSA-176407 Reactome: R-HSA-176408 Reactome: R-HSA-176409 Reactome: R-HSA-176412 Reactome: R-HSA-179409 Reactome: R-HSA-2467813 Reactome: R-HSA-2559582 Reactome: R-HSA-68867 Reactome: R-HSA-69017 Reactome: R-HSA-8853884 Reactome: R-HSA-9687136 Reactome: R-HSA-983168
Cellular Localisation	Cytoplasm Cytoskeleton Microtubule Organizing Center Centrosome Spindle Colocalizes With Cdc27 To The Centrosome At All Stages Of The Cell Cycle And To The Mitotic Spindle
Alternative Antibody Names	Anti-Cell Division Cycle Protein 16 Homolog antibody Anti-Anaphase-Promoting Complex Subunit 6 antibody Anti-Apc6 antibody Anti-Cdc16 Homolog antibody Anti-Cdc16hs antibody Anti-Cyclosome Subunit 6 antibody Anti-CDC16 antibody Anti-ANAPC6 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-CDC16 antibody (371-620) (STJ29277)