Anti-CDC23 antibody (498-597) [S7MR] (STJ11103607) STJ11103607 上海玉博生物科技有限公司

Anti-CDC23 antibody (498-597) [S7MR] (STJ11103607)

简单介绍

Anti-CDC23 antibody (498-597) [S7MR] (STJ11103607)

产品描述

Host:	Rabbit
Applications:	WB/IF
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit monoclonal antibody anti-CDC23 (498-597) is suitable for use in Western Blot and Immunofluorescence research applications.

Clonality:	Monoclonal
Clone ID:	S7MR
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000 IF/ICC 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CDC23
Gene ID:	8697
Uniprot ID:	CDC23_HUMAN
Immunogen Region:	498-597
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 498-597 of human CDC23 (Q9UJX2).
Immunogen Sequence:	YSCGEIVEHLEESTAFRYLA QYYFKCKLWDEASTCAQKCC AFNDTREEGKALLRQILQLR NQGETPTTEVPAPFFLPASL SANNTPTRRVSPLNLSSVTP

Post Translational Modifications	Phosphorylated. Phosphorylation on Thr-562 occurs specifically during mitosis.
Function	Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Protein Name	Cell Division Cycle Protein 23 Homolog Anaphase-Promoting Complex Subunit 8 Apc8 Cyclosome Subunit 8
Database Links	Reactome: R-HSA-141430 Reactome: R-HSA-174048 Reactome: R-HSA-174084 Reactome: R-HSA-174154 Reactome: R-HSA-174178 Reactome: R-HSA-174184 Reactome: R-HSA-176407 Reactome: R-HSA-176408 Reactome: R-HSA-176409 Reactome: R-HSA-176412 Reactome: R-HSA-179409 Reactome: R-HSA-2467813 Reactome: R-HSA-2559582 Reactome: R-HSA-68867 Reactome: R-HSA-69017 Reactome: R-HSA-8853884 Reactome: R-HSA-9687136 Reactome: R-HSA-983168
Alternative Antibody Names	Anti-Cell Division Cycle Protein 23 Homolog antibody Anti-Anaphase-Promoting Complex Subunit 8 antibody Anti-Apc8 antibody Anti-Cyclosome Subunit 8 antibody Anti-CDC23 antibody Anti-ANAPC8 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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