Human PRDX1 (Peroxiredoxin 1) Sandwich ELISA Kit Ready-To-Use (STJE0018029) STJE0018029 上海玉博生物科技有限公司

Human PRDX1 (Peroxiredoxin 1) Sandwich ELISA Kit Ready-To-Use (STJE0018029)

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产品名称：Human PRDX1 (Peroxiredoxin 1) Sandwich ELISA Kit Ready-To-Use (STJE0018029)
产品型号：STJE0018029
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human PRDX1 (Peroxiredoxin 1) Sandwich ELISA Kit Ready-To-Use (STJE0018029)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.126ng/mL
Detection Limit:	0.312-20ng/mL
Short Description:	This PRDX1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	PRDX1
Gene ID:	5052
Uniprot ID:	PRDX1_HUMAN
Immunogen Region:	Ready-To-Use
Sample Type:	serum, plasma, tissue homogenates, cell lysates or other biological fluids.

Tissue Specificity
Post Translational Modifications	Phosphorylated on Thr-90 during the M-phase, which leads to a more than 80% decrease in enzymatic activity. The enzyme can be inactivated by further oxidation of the cysteine sulfenic acid (C(P)-SOH) to sulphinic acid (C(P)-SO2H) instead of its condensation to a disulfide bond. It can be reactivated by forming a transient disulfide bond with sulfiredoxin SRXN1, which reduces the cysteine sulfinic acid in an ATP- and Mg-dependent manner.
Function	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation.
Protein Name	Peroxiredoxin-1 Natural Killer Cell-Enhancing Factor A Nkef-A Proliferation-Associated Gene Protein Pag Thioredoxin Peroxidase 2 Thioredoxin-Dependent Peroxide Reductase 2 Thioredoxin-Dependent Peroxiredoxin 1
Database Links	Reactome: R-HSA-3299685 Reactome: R-HSA-5628897 Reactome: R-HSA-8862803 Reactome: R-HSA-9818027
Cellular Localisation	Cytoplasm Melanosome Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv
Alternative ELISA Names	Peroxiredoxin-1 ELISA kit Natural Killer Cell-Enhancing Factor A ELISA kit Nkef-A ELISA kit Proliferation-Associated Gene Protein ELISA kit Pag ELISA kit Thioredoxin Peroxidase 2 ELISA kit Thioredoxin-Dependent Peroxide Reductase 2 ELISA kit Thioredoxin-Dependent Peroxiredoxin 1 ELISA kit PRDX1 ELISA kit PAGA ELISA kit PAGB ELISA kit TDPX2 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Human PRDX1 (Peroxiredoxin 1) Sandwich ELISA Kit Ready-To-Use (STJE0018029)