Anti-CDK11B antibody (1-130) (STJ116915) STJ116915 上海玉博生物科技有限公司

Anti-CDK11B antibody (1-130) (STJ116915)

简单介绍

Anti-CDK11B antibody (1-130) (STJ116915)

产品描述

Host:	Rabbit
Applications:	IF
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CDK11B (1-130) is suitable for use in Immunofluorescence research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	IF/ICC 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CDK11B
Gene ID:	984
Uniprot ID:	CD11B_HUMAN
Immunogen Region:	1-130
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human CDK11B (NP_277021.2).
Immunogen Sequence:	MGDEKDSWKVKTLDEILQEK KRRKEQEEKAEIKRLKNSDD RDSKRDSLEEGELRDHRMEI TIRNSPYRREDSMEDRGEED DSLAIKPPQQMSRKEKAHHR KDEKRKEKRRHRSHSAEGGK HARVKEKERE

Tissue Specificity	Expressed ubiquitously. Some evidence of isoform-specific tissue distribution.
Post Translational Modifications	During FAS- or TNF-induced apoptosis, isoform SV9 is cleaved by caspases to produce p110C, a fragment that contains the C-terminal kinase domain. Phosphorylation at Ser-115 creates a binding site for 14-3-3 proteins. p110C can be autophosphorylated.
Function	Plays multiple roles in cell cycle progression, cytokinesis and apoptosis. Involved in pre-mRNA splicing in a kinase activity-dependent manner. Isoform 7 may act as a negative regulator of normal cell cycle progression.
Protein Name	Cyclin-Dependent Kinase 11b Cell Division Cycle 2-Like Protein Kinase 1 Clk-1 Cell Division Protein Kinase 11b Galactosyltransferase-Associated Protein Kinase P58/Gta Pitslre Serine/Threonine-Protein Kinase Cdc2l1 P58 Clk-1
Database Links	Reactome: R-HSA-380270
Cellular Localisation	Cytoplasm Nucleus
Alternative Antibody Names	Anti-Cyclin-Dependent Kinase 11b antibody Anti-Cell Division Cycle 2-Like Protein Kinase 1 antibody Anti-Clk-1 antibody Anti-Cell Division Protein Kinase 11b antibody Anti-Galactosyltransferase-Associated Protein Kinase P58/Gta antibody Anti-Pitslre Serine/Threonine-Protein Kinase Cdc2l1 antibody Anti-P58 Clk-1 antibody Anti-CDK11B antibody Anti-CDC2L1 antibody Anti-CDK11 antibody Anti-PITSLREA antibody Anti-PK58 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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