Human RNASEN (Ribonuclease III, Nuclear) Sandwich ELISA Kit Ready-To-Use (STJE0018305) STJE0018305 上海玉博生物科技有限公司

Human RNASEN (Ribonuclease III, Nuclear) Sandwich ELISA Kit Ready-To-Use (STJE0018305)

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产品名称：Human RNASEN (Ribonuclease III, Nuclear) Sandwich ELISA Kit Ready-To-Use (STJE0018305)
产品型号：STJE0018305
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human RNASEN (Ribonuclease III, Nuclear) Sandwich ELISA Kit Ready-To-Use (STJE0018305)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.126ng/mL
Detection Limit:	0.312-20ng/mL
Short Description:	This RNASEN Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	DROSHA
Gene ID:	29102
Uniprot ID:	RNC_HUMAN
Immunogen Region:	Ready-To-Use
Sample Type:	tissue homogenates, cell lysates or other biological fluids.

Tissue Specificity	Ubiquitous.
Post Translational Modifications
Function	Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA-ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies.
Protein Name	Ribonuclease 3 Protein Drosha Ribonuclease Iii Rnase Iii P241
Database Links	Reactome: R-HSA-203927
Cellular Localisation	Nucleus Nucleolus A Fraction Is Translocated To The Nucleolus During The S Phase Of The Cell Cycle Localized In Gw Bodies (Gwbs) Also Known As P-Bodies
Alternative ELISA Names	Ribonuclease 3 ELISA kit Protein Drosha ELISA kit Ribonuclease Iii ELISA kit Rnase Iii ELISA kit P241 ELISA kit DROSHA ELISA kit RN3 ELISA kit RNASE3L ELISA kit RNASEN ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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