Human RNLS (Renalase) Sandwich ELISA Kit (STJE0011923) STJE0011923 上海玉博生物科技有限公司

Human RNLS (Renalase) Sandwich ELISA Kit (STJE0011923)

简单介绍

Human RNLS (Renalase) Sandwich ELISA Kit (STJE0011923)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.52ng/mL
Detection Limit:	1.25-80ng/mL
Short Description:	This RNLS Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	RNLS
Gene ID:	55328
Uniprot ID:	RNLS_HUMAN
Sample Type:	serum, plasma or other biological fluids.

Tissue Specificity	Secreted into the blood by the kidney. Highly expressed in the kidney, expressed at lower level in heart, skeletal muscle and small intestine. Its plasma concentration is markedly reduced in patients with end-stage renal disease, as compared with healthy subjects.
Post Translational Modifications
Function	Catalyzes the oxidation of the less abundant 1,2-dihydro-beta-NAD(P) and 1,6-dihydro-beta-NAD(P) to form beta-NAD(P)(+). The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.
Protein Name	Renalase Monoamine Oxidase-C Mao-C
Database Links	Reactome: R-HSA-197264
Cellular Localisation	Secreted
Alternative ELISA Names	Renalase ELISA kit Monoamine Oxidase-C ELISA kit Mao-C ELISA kit RNLS ELISA kit C10orf59 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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