Anti-CENPQ antibody (131-268) (STJ29765) STJ29765 上海玉博生物科技有限公司

Anti-CENPQ antibody (131-268) (STJ29765)

简单介绍

Anti-CENPQ antibody (131-268) (STJ29765)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CENPQ (131-268) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CENPQ
Gene ID:	55166
Uniprot ID:	CENPQ_HUMAN
Immunogen Region:	131-268
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 131-268 of human CENPQ (NP_060602.2).
Immunogen Sequence:	MEDLTNVSSLLNMERARDKA NEEGLALLQEEIDKMVETTE LMTGNIQSLKNKIQILASEV EEEEERVKQMHQINSSGVLS LPELSQKTLKAPTLQKEILA LIPNQNALLKDLDILHNSSQ MKSMSTFIEEAYKKLDAS

Post Translational Modifications	Phosphorylation at Ser-50 is essential for CENPE recruitment to kinetochores and orderly chromosome congression.
Function	Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Plays an important role in chromosome congression and in the recruitment of CENP-O complex (which comprises CENPO, CENPP, CENPQ and CENPU), CENPE and PLK1 to the kinetochores.
Protein Name	Centromere Protein Q Cenp-Q
Database Links	Reactome: R-HSA-141444 Reactome: R-HSA-2467813 Reactome: R-HSA-2500257 Reactome: R-HSA-5663220 Reactome: R-HSA-606279 Reactome: R-HSA-68877 Reactome: R-HSA-9648025
Cellular Localisation	Nucleus Chromosome Centromere Localizes Exclusively In The Centromeres The Cenpa-Cad Complex Is Probably Recruited On Centromeres By The Cenpa-Nac Complex
Alternative Antibody Names	Anti-Centromere Protein Q antibody Anti-Cenp-Q antibody Anti-CENPQ antibody Anti-C6orf139 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

产品目录