Anti-CENPT antibody (20-100 aa) (STJ191688) STJ191688 上海玉博生物科技有限公司

Anti-CENPT antibody (20-100 aa) (STJ191688)

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产品名称：Anti-CENPT antibody (20-100 aa) (STJ191688)
产品型号：STJ191688
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-CENPT antibody (20-100 aa) (STJ191688)

产品描述

Host:	Rabbit
Applications:	WB/ELISA
Reactivity:	Human/Rat/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Centromere protein T (20-100 aa) is suitable for use in Western Blot and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-2000 ELISA 1:5000-20000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CENPT
Gene ID:	80152
Uniprot ID:	CENPT_HUMAN
Immunogen Region:	20-100 aa
Specificity:	CENPT Polyclonal Antibody detects endogenous levels of protein.
Immunogen:	Synthesized peptide derived from the human protein at the amino acid range 20-100

Function	Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. CENPT has a fundamental role in kinetochore assembly and function. It is one of the inner kinetochore proteins, with most further proteins binding downstream. Required for normal chromosome organization and normal progress through mitosis.
Protein Name	Centromere Protein T Cenp-T Interphase Centromere Complex Protein 22
Database Links	Reactome: R-HSA-141444 Reactome: R-HSA-2467813 Reactome: R-HSA-2500257 Reactome: R-HSA-5663220 Reactome: R-HSA-606279 Reactome: R-HSA-68877 Reactome: R-HSA-9648025
Cellular Localisation	Nucleus Chromosome Centromere Kinetochore Constitutively Localizes To Centromeres Throughout The Cell Cycle And To Kinetochores During Mitosis Localizes To The Inner Kinetochore And May Connect It To The Outer Kinetochore Via Its N-Terminus
Alternative Antibody Names	Anti-Centromere Protein T antibody Anti-Cenp-T antibody Anti-Interphase Centromere Complex Protein 22 antibody Anti-CENPT antibody Anti-C16orf56 antibody Anti-ICEN22 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-CENPT antibody (20-100 aa) (STJ191688)