Anti-CEP135 antibody (841-1140) (STJ117559) STJ117559 上海玉博生物科技有限公司

Anti-CEP135 antibody (841-1140) (STJ117559)

简单介绍

Anti-CEP135 antibody (841-1140) (STJ117559)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CEP135 (841-1140) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:200-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CEP135
Gene ID:	9662
Uniprot ID:	CP135_HUMAN
Immunogen Region:	841-1140
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 841-1140 of human CEP135 (NP_079285.2).
Immunogen Sequence:	LEAAVQEKEEMKSRVHKYIT EVSRWESLMAAKEKENQDLL DRFQMLHNRAEDWEVKAHQA EGESSSVRLELLSIDTERRH LRERVELLEKEIQEHINAHH AYESQISSMAKAMSRLEEEL RHQEDEKATVLNDLSSLREL CIKLDSGKDIMTQQLNSKNL EFERVVVELENVKSESDLLK KQLSNERHTVKNLESLLATN RDKEFHSHLTSHEKDTEIQL LKEKLTLSESKLTSQSREN

Function	Centrosomal protein involved in centriole biogenesis. Acts as a scaffolding protein during early centriole biogenesis. Required for the targeting of centriole satellite proteins to centrosomes such as of PCM1, SSX2IP and CEP290 and recruitment of WRAP73 to centrioles. Also required for centriole-centriole cohesion during interphase by acting as a platform protein for CEP250 at the centriole. Required for the recruitment of CEP295 to the proximal end of new-born centrioles at the centriolar microtubule wall during early S phase in a PLK4-dependent manner.
Protein Name	Centrosomal Protein Of 135 Kda Cep135 Centrosomal Protein 4
Database Links	Reactome: R-HSA-2565942 Reactome: R-HSA-380259 Reactome: R-HSA-380270 Reactome: R-HSA-380284 Reactome: R-HSA-380320 Reactome: R-HSA-5620912 Reactome: R-HSA-8854518
Cellular Localisation	Cytoplasm Cytoskeleton Microtubule Organizing Center Centrosome Centriole During Centriole Biogenesis It Is Concentrated Within The Proximal Lumen Of Both Parental Centrioles And Procentrioles
Alternative Antibody Names	Anti-Centrosomal Protein Of 135 Kda antibody Anti-Cep135 antibody Anti-Centrosomal Protein 4 antibody Anti-CEP135 antibody Anti-CEP4 antibody Anti-KIAA0635 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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