Anti-CERK antibody (C-Term) (STJ118334) STJ118334 上海玉博生物科技有限公司

Anti-CERK antibody (C-Term) (STJ118334)

简单介绍

Anti-CERK antibody (C-Term) (STJ118334)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CERK (C-Term) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CERK
Gene ID:	64781
Uniprot ID:	CERK1_HUMAN
Immunogen Region:	C-Term
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 400 to the C-terminus of human CERK (NP_073603.2).
Immunogen Sequence:	CRRSPRGLSPAAHLGDGSSD LILIRKCSRFNFLRFLIRHT NQQDQFDFTFVEVYRVKKFQ FTSKHMEDEDSDLKEGGKKR FGHICSSHPSCCCTVSNSSW NCDGEVLHSPAIEVRVHCQL VRLFARGIEENPKPDSHS

Tissue Specificity	High level expression in heart, brain, skeletal muscle, kidney and liver.moderate in peripheral blood leukocytes and thymus.very low in spleen, small intestine, placenta and lung.
Function	Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Shows a greater preference for D-erythro isomer of ceramides. Binds phosphoinositides.
Protein Name	Ceramide Kinase Hcerk Acylsphingosine Kinase Lipid Kinase 4 Lk4
Database Links	Reactome: R-HSA-1660662
Cellular Localisation	Cytoplasm Cell Membrane Peripheral Membrane Protein
Alternative Antibody Names	Anti-Ceramide Kinase antibody Anti-Hcerk antibody Anti-Acylsphingosine Kinase antibody Anti-Lipid Kinase 4 antibody Anti-Lk4 antibody Anti-CERK antibody Anti-KIAA1646 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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