Anti-CERS2 antibody (STJA0007270) STJA0007270 上海玉博生物科技有限公司

Anti-CERS2 antibody (STJA0007270)

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产品名称：Anti-CERS2 antibody (STJA0007270)
产品型号：STJA0007270
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-CERS2 antibody (STJA0007270)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Ceramide synthase 2 is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CERS2
Gene ID:	29956
Uniprot ID:	CERS2_HUMAN
Specificity:	This antibody detects endogenous levels of LASS2 at Human, Mouse
Immunogen:	Synthesized peptide derived from human LASS2

Post Translational Modifications	Acetylated. Deacetylation by SIRT3 increases enzyme activity and promotes mitochondrial ceramide accumulation. Phosphorylated at the C-terminus by CK2, leading to increase the ceramide synthase activity.
Function	Ceramide synthase that catalyzes the transfer of the acyl chain from acyl-CoA to a sphingoid base, with high selectivity toward very-long-chain fatty acyl-CoA (chain length C22-C27). N-acylates sphinganine and sphingosine bases to form dihydroceramides and ceramides in de novo synthesis and salvage pathways, respectively. Plays a non-redundant role in the synthesis of ceramides with very-long-chain fatty acids in kidney, liver and brain. Regulates the abundance of myelin-specific sphingolipids galactosylceramide and sulfatide that affects myelin sheath architecture and motor neuron functions.
Protein Name	Ceramide Synthase 2 Cers2 Lag1 Longevity Assurance Homolog 2 Sp260 Sphingosine N-Acyltransferase Cers2 Tumor Metastasis-Suppressor Gene 1 Protein Very-Long-Chain Ceramide Synthase Cers2
Database Links	Reactome: R-HSA-1660661
Cellular Localisation	Endoplasmic Reticulum Membrane Multi-Pass Membrane Protein
Alternative Antibody Names	Anti-Ceramide Synthase 2 antibody Anti-Cers2 antibody Anti-Lag1 Longevity Assurance Homolog 2 antibody Anti-Sp260 antibody Anti-Sphingosine N-Acyltransferase Cers2 antibody Anti-Tumor Metastasis-Suppressor Gene 1 Protein antibody Anti-Very-Long-Chain Ceramide Synthase Cers2 antibody Anti-CERS2 antibody Anti-LASS2 antibody Anti-TMSG1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-CERS2 antibody (STJA0007270)