Anti-Ceruloplasmin antibody (366-572) [S2MR] (STJ11103232) STJ11103232 上海玉博生物科技有限公司

Anti-Ceruloplasmin antibody (366-572) [S2MR] (STJ11103232)

简单介绍

Anti-Ceruloplasmin antibody (366-572) [S2MR] (STJ11103232)

产品描述

Host:	Rabbit
Applications:	WB/IHC/IF
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit monoclonal antibody anti-Ceruloplasmin (366-572) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.

Clonality:	Monoclonal
Clone ID:	S2MR
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 0.05% BSA, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:1000-1:5000 IHC-P 1:50-1:200 IF/ICC 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CP
Gene ID:	1356
Uniprot ID:	CERU_HUMAN
Immunogen Region:	366-572
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 366-572 of human Ceruloplasmin (NP_000087.1).
Immunogen Sequence:	IRGKHVRHYYIAAEEIIWNY APSGIDIFTKENLTAPGSDS AVFFEQGTTRIGGSYKKLVY REYTDASFTNRKERGPEEEH LGILGPVIWAEVGDTIRVTF HNKGAYPLSIEPIGVRFNKN NEGTYYSPNYNPQSRSVPPS ASHVAPTETFTYEWTVPKEV GPTNADPVCLAKMYYSAVDP TKDIFTGLIGPMKICKKGSL HANGRQK

Tissue Specificity	Expressed by the liver and secreted in plasma.
Function	Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the cell membrane. Provides Cu(2+) ions for the ascorbate-mediated deaminase degradation of the heparan sulfate chains of GPC1. May also play a role in fetal lung development or pulmonary antioxidant defense.
Protein Name	Ceruloplasmin Ferroxidase
Database Links	Reactome: R-HSA-381426 Reactome: R-HSA-425410 Reactome: R-HSA-5619049 Reactome: R-HSA-5619060 Reactome: R-HSA-8957275 Reactome: R-HSA-917937
Cellular Localisation	Secreted Colocalizes With Gcp1 In Secretory Intracellular Compartments
Alternative Antibody Names	Anti-Ceruloplasmin antibody Anti-Ferroxidase antibody Anti-CP antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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