Anti-CES3 antibody (269-568) (STJ116247) STJ116247 上海玉博生物科技有限公司

Anti-CES3 antibody (269-568) (STJ116247)

简单介绍

Anti-CES3 antibody (269-568) (STJ116247)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CES3 (269-568) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CES3
Gene ID:	23491
Uniprot ID:	EST3_HUMAN
Immunogen Region:	269-568
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 269-568 of human CES3 (NP_001172106.1).
Immunogen Sequence:	WPLAQKIANTLACSSSSPAE MVQCLQQKEGEELVLSKKLK NTIYPLTVDGTVFPKSPKEL LKEKPFHSVPFLMGVNNHEF SWLIPRGWGLLDTMEQMSRE DMLAISTPVLTSLDVPPEMM PTVIDEYLGSNSDAQAKCQA FQEFMGDVFINVPTVSFSRY LRDSGSPVFFYEFQHRPSSF AKIKPAWVKADHGAEGAFVF GGPFLMDESSRLEATEEEKQ LSLTMMAQWTHFARTGDPN

Tissue Specificity	Expressed in liver, colon and small intestine.
Post Translational Modifications	N-glycosylated.
Function	Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows low catalytic efficiency for hydrolysis of CPT-11 (7-ethyl-10-4-(1-piperidino)-1-piperidino-carbonyloxycamptothecin), a prodrug for camptothecin used in cancer therapeutics.
Protein Name	Carboxylesterase 3 Liver Carboxylesterase 31 Homolog
Database Links	Reactome: R-HSA-211945 Reactome: R-HSA-8964038
Cellular Localisation	Endoplasmic Reticulum Lumen
Alternative Antibody Names	Anti-Carboxylesterase 3 antibody Anti-Liver Carboxylesterase 31 Homolog antibody Anti-CES3 antibody Anti-UNQ869 antibody Anti-PRO1887 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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