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> Human SCNN1b (Amiloride Sensitive Sodium Channel Subunit Beta) Sandwich ELISA Kit Ready-To-Use (STJE0018429)

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Human SCNN1b (Amiloride Sensitive Sodium Channel Subunit Beta) Sandwich ELISA Kit Ready-To-Use (STJE0018429)

Human SCNN1b (Amiloride Sensitive Sodium Channel Subunit Beta) Sandwich ELISA Kit Ready-To-Use (STJE0018429)
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  • 产品名称:Human SCNN1b (Amiloride Sensitive Sodium Channel Subunit Beta) Sandwich ELISA Kit Ready-To-Use (STJE0018429)
  • 产品型号:STJE0018429
  • 产品展商:ST john's laboratory
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简单介绍
Human SCNN1b (Amiloride Sensitive Sodium Channel Subunit Beta) Sandwich ELISA Kit Ready-To-Use (STJE0018429)
产品描述
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.107ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This SCNN1b Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: SCNN1B
Gene ID: 6338
Uniprot ID: SCNNB_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Detected in placenta, lung and kidney. Expressed in kidney (at protein level).
Post Translational Modifications Phosphorylated on serine and threonine residues. Aldosterone and insulin increase the basal level of phosphorylation. N-glycosylated. N-glycosylation is required for interaction with BPIFA1.
Function Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
Protein Name Amiloride-Sensitive Sodium Channel Subunit Beta
Beta-Nach
Epithelial Na(+ Channel Subunit Beta
Beta-Enac
Enacb
Nonvoltage-Gated Sodium Channel 1 Subunit Beta
Scneb
Database Links Reactome: R-HSA-2672351
Reactome: R-HSA-9730628
Cellular Localisation Apical Cell Membrane
Multi-Pass Membrane Protein
Cytoplasmic Vesicle Membrane
Apical Membrane Of Epithelial Cells
Alternative ELISA Names Amiloride-Sensitive Sodium Channel Subunit Beta ELISA kit
Beta-Nach ELISA kit
Epithelial Na(+ Channel Subunit Beta ELISA kit
Beta-Enac ELISA kit
Enacb ELISA kit
Nonvoltage-Gated Sodium Channel 1 Subunit Beta ELISA kit
Scneb ELISA kit
SCNN1B ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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