Anti-CFB antibody (26-764) (STJ11105589) STJ11105589 上海玉博生物科技有限公司

Anti-CFB antibody (26-764) (STJ11105589)

简单介绍

Anti-CFB antibody (26-764) (STJ11105589)

产品描述

Host:	Rabbit
Applications:	WB/IF
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Complement Factor B (26-764) is suitable for use in Western Blot and Immunofluorescence research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:1000 IF/ICC 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CFB
Gene ID:	629
Uniprot ID:	CFAB_HUMAN
Immunogen Region:	26-764
Immunogen:	Recombinant Protein corresponding to a sequence within amino acids 26-764 of human Complement factor B (NP_001701.2).
Immunogen Sequence:	TPWSLARPQGSCSLEGVEIK GGSFRLLQEGQALEYVCPSG FYPYPVQTRTCRSTGSWSTL KTQDQKTVRKAECRAIHCPR PHDFENGEYWPRSPYYNVSD EISFHCYDGYTLRGSANRTC QVNGRWSGQTAICDNGAGYC SNPGIPIGTRKVGSQYRLED SVTYHCSRGLTLRGSQRRTC QEGGSWSGTEPSCQDSFMYD TPQEVAEAFLSSLTETIEGV DAEDGHGPGEQQKRKIVLD

Function	Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
Protein Name	Complement Factor B C3/C5 Convertase Glycine-Rich Beta Glycoprotein Gbg Pbf2 Properdin Factor B Cleaved Into - Complement Factor B Ba Fragment - Complement Factor B Bb Fragment
Database Links	Reactome: R-HSA-173736 Reactome: R-HSA-174577 Reactome: R-HSA-977606
Cellular Localisation	Secreted
Alternative Antibody Names	Anti-Complement Factor B antibody Anti-C3/C5 Convertase antibody Anti-Glycine-Rich Beta Glycoprotein antibody Anti-Gbg antibody Anti-Pbf2 antibody Anti-Properdin Factor B Cleaved Into - Complement Factor B Ba Fragment - Complement Factor B Bb Fragment antibody Anti-CFB antibody Anti-BF antibody Anti-BFD antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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