Human SETD7 (SET Domain Containing Protein 7) Sandwich ELISA Kit (STJE0012115) STJE0012115 上海玉博生物科技有限公司

Human SETD7 (SET Domain Containing Protein 7) Sandwich ELISA Kit (STJE0012115)

如果您对该产品感兴趣的话，可以
产品名称：Human SETD7 (SET Domain Containing Protein 7) Sandwich ELISA Kit (STJE0012115)
产品型号：STJE0012115
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human SETD7 (SET Domain Containing Protein 7) Sandwich ELISA Kit (STJE0012115)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.054ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This SETD7 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	SETD7
Gene ID:	80854
Uniprot ID:	SETD7_HUMAN
Sample Type:	tissue homogenates or other biological fluids.

Tissue Specificity	Widely expressed. Expressed in pancreatic islets.
Post Translational Modifications
Function	Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as CGAS, p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the KR-STA-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation. Monomethylates 'Lys-491' of CGAS, promoting interaction between SGF29 and CGAS.
Protein Name	Histone-Lysine N-Methyltransferase Setd7 Histone H3-K4 Methyltransferase Setd7 H3-K4-Hmtase Setd7 Lysine N-Methyltransferase 7 Set Domain-Containing Protein 7 Set7/9
Database Links	Reactome: R-HSA-3214841
Cellular Localisation	Nucleus Chromosome
Alternative ELISA Names	Histone-Lysine N-Methyltransferase Setd7 ELISA kit Histone H3-K4 Methyltransferase Setd7 ELISA kit H3-K4-Hmtase Setd7 ELISA kit Lysine N-Methyltransferase 7 ELISA kit Set Domain-Containing Protein 7 ELISA kit Set7/9 ELISA kit SETD7 ELISA kit KIAA1717 ELISA kit KMT7 ELISA kit SET7 ELISA kit SET9 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

温馨提示：为规避购买风险，建议您在购买前务必确认供应商资质与产品质量。
免责申明：以上内容为注册会员自行发布，若信息的真实性、合法性存在争议，平台将会监督协助处理，欢迎举报

产品目录

产品资料

Human SETD7 (SET Domain Containing Protein 7) Sandwich ELISA Kit (STJE0012115)