Anti-CHD3 antibody (1-100) [S6MR] (STJ11102316) STJ11102316 上海玉博生物科技有限公司

Anti-CHD3 antibody (1-100) [S6MR] (STJ11102316)

简单介绍

Anti-CHD3 antibody (1-100) [S6MR] (STJ11102316)

产品描述

Host:	Rabbit
Applications:	WB/IHC/IF
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit monoclonal antibody anti-CHD3 (1-100) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.

Clonality:	Monoclonal
Clone ID:	S6MR
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:1000 IHC-P 1:50-1:200 IF/ICC 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CHD3
Gene ID:	1107
Uniprot ID:	CHD3_HUMAN
Immunogen Region:	1-100
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CHD3 (Q12873).
Immunogen Sequence:	MKAADTVILWARSKNDQLRI SFPPGLCWGDRMPDKDDIRL LPSALGVKKRKRGPKKQKEN KPGKPRKRKKRDSEEEFGSE RDEYREKSESGGSEYGTGPG

Tissue Specificity	Widely expressed.
Post Translational Modifications	Sumoylation at Lys-1971 results in dissociation from chromatin and suppression of transcriptional repression.
Function	ATP-dependent helicase that binds and distorts nucleosomal DNA. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Involved in transcriptional repression as part of the NuRD complex. Required for anchoring centrosomal pericentrin in both interphase and mitosis, for spindle organization and centrosome integrity.
Protein Name	Chromodomain-Helicase-Dna-Binding Protein 3 Chd-3 Atp-Dependent Helicase Chd3 Mi-2 Autoantigen 240 Kda Protein Mi2-Alpha Zinc Finger Helicase Hzfh
Database Links	Reactome: R-HSA-3214815 Reactome: R-HSA-427389 Reactome: R-HSA-4551638 Reactome: R-HSA-6804758 Reactome: R-HSA-73762 Reactome: R-HSA-8943724 Reactome: R-HSA-9679191
Cellular Localisation	Nucleus Pml Body Cytoplasm Cytoskeleton Microtubule Organizing Center Centrosome Associates With Centrosomes In Interphase And Mitosis Localizes To Sites Of Dna Damage
Alternative Antibody Names	Anti-Chromodomain-Helicase-Dna-Binding Protein 3 antibody Anti-Chd-3 antibody Anti-Atp-Dependent Helicase Chd3 antibody Anti-Mi-2 Autoantigen 240 Kda Protein antibody Anti-Mi2-Alpha antibody Anti-Zinc Finger Helicase antibody Anti-Hzfh antibody Anti-CHD3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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