Anti-CHD4 antibody (571-620 aa) (STJ94119) STJ94119 上海玉博生物科技有限公司

Anti-CHD4 antibody (571-620 aa) (STJ94119)

简单介绍

Anti-CHD4 antibody (571-620 aa) (STJ94119)

产品描述

Host:	Rabbit
Applications:	IHC/IF/ELISA
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Chromodomain-helicase-DNA-binding protein 4 (571-620 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:20000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CHD4
Gene ID:	1108
Uniprot ID:	CHD4_HUMAN
Immunogen Region:	571-620 aa
Specificity:	Mi2-Beta Polyclonal Antibody detects endogenous levels of Mi2-Beta protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human CHD4 at the amino acid range 571-620

Function	ATP-dependent helicase that binds and distorts nucleosomal DNA. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Localizes to acetylated damaged chromatin in a ZMYND8-dependent manner, to promote transcriptional repression and double-strand break repair by homologous recombination. Involved in neurogenesis.
Protein Name	Chromodomain-Helicase-Dna-Binding Protein 4 Chd-4 Atp-Dependent Helicase Chd4 Mi-2 Autoantigen 218 Kda Protein Mi2-Beta
Database Links	Reactome: R-HSA-3214815 Reactome: R-HSA-427389 Reactome: R-HSA-6804758 Reactome: R-HSA-73762 Reactome: R-HSA-8943724 Reactome: R-HSA-9031628 Reactome: R-HSA-9679191
Cellular Localisation	Nucleus Cytoplasm Cytoskeleton Microtubule Organizing Center Centrosome Associates With Centrosomes In Interphase Localizes To Sites Of Dna Damage In A Manner Dependent On Zmynd8 And Znf687
Alternative Antibody Names	Anti-Chromodomain-Helicase-Dna-Binding Protein 4 antibody Anti-Chd-4 antibody Anti-Atp-Dependent Helicase Chd4 antibody Anti-Mi-2 Autoantigen 218 Kda Protein antibody Anti-Mi2-Beta antibody Anti-CHD4 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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