Human SGLT1 (Sodium/Glucose Cotransporter 1) Sandwich ELISA Kit Ready-To-Use (STJE0018523) STJE0018523 上海玉博生物科技有限公司

Human SGLT1 (Sodium/Glucose Cotransporter 1) Sandwich ELISA Kit Ready-To-Use (STJE0018523)

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产品名称：Human SGLT1 (Sodium/Glucose Cotransporter 1) Sandwich ELISA Kit Ready-To-Use (STJE0018523)
产品型号：STJE0018523
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human SGLT1 (Sodium/Glucose Cotransporter 1) Sandwich ELISA Kit Ready-To-Use (STJE0018523)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.056ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This SGLT1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	SLC5A1
Gene ID:	6523
Uniprot ID:	SC5A1_HUMAN
Immunogen Region:	Ready-To-Use
Sample Type:	tissue homogenates or other biological fluids.

Tissue Specificity	Expressed in intestine. Expressed in endometrial cells.
Post Translational Modifications	N-glycosylation is not necessary for the cotransporter function.
Function	Electrogenic Na(+)-coupled sugar simporter that actively transports D-glucose or D-galactose at the plasma membrane, with a Na(+) to sugar coupling ratio of 2:1. Transporter activity is driven by a transmembrane Na(+) electrochemical gradient set by the Na(+)/K(+) pump. Has a primary role in the transport of dietary monosaccharides from enterocytes to blood. Responsible for the absorption of D-glucose or D-galactose across the apical brush-border membrane of enterocytes, whereas basolateral exit is provided by GLUT2. Additionally, functions as a D-glucose sensor in enteroendocrine cells, triggering the secretion of the incretins GCG and GIP that control food intake and energy homeostasis. Together with SGLT2, functions in reabsorption of D-glucose from glomerular filtrate, playing a nonredundant role in the S3 segment of the proximal tubules. Transports D-glucose into endometrial epithelial cells, controlling glycogen synthesis and nutritional support for the embryo as well as the decidual transformation of endometrium prior to conception. Acts as a water channel enabling passive water transport across the plasma membrane in response to the osmotic gradient created upon sugar and Na(+) uptake. Has high water conductivity, comparable to aquaporins, and therefore is expected to play an important role in transepithelial water permeability, especially in the small intestine.
Protein Name	Sodium/Glucose Cotransporter 1 Na(+/Glucose Cotransporter 1 High Affinity Sodium-Glucose Cotransporter Solute Carrier Family 5 Member 1
Database Links	Reactome: R-HSA-189200 Reactome: R-HSA-5656364 Reactome: R-HSA-8981373
Cellular Localisation	Apical Cell Membrane Multi-Pass Membrane Protein
Alternative ELISA Names	Sodium/Glucose Cotransporter 1 ELISA kit Na(+/Glucose Cotransporter 1 ELISA kit High Affinity Sodium-Glucose Cotransporter ELISA kit Solute Carrier Family 5 Member 1 ELISA kit SLC5A1 ELISA kit NAGT ELISA kit SGLT1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Human SGLT1 (Sodium/Glucose Cotransporter 1) Sandwich ELISA Kit Ready-To-Use (STJE0018523)