Human SKP1 (S-Phase Kinase Associated Protein 1) Sandwich ELISA Kit Ready-To-Use (STJE0018569) STJE0018569 上海玉博生物科技有限公司

Human SKP1 (S-Phase Kinase Associated Protein 1) Sandwich ELISA Kit Ready-To-Use (STJE0018569)

如果您对该产品感兴趣的话，可以
产品名称：Human SKP1 (S-Phase Kinase Associated Protein 1) Sandwich ELISA Kit Ready-To-Use (STJE0018569)
产品型号：STJE0018569
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human SKP1 (S-Phase Kinase Associated Protein 1) Sandwich ELISA Kit Ready-To-Use (STJE0018569)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.054ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This SKP1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	SKP1
Gene ID:	6500
Uniprot ID:	SKP1_HUMAN
Immunogen Region:	Ready-To-Use
Sample Type:	tissue homogenates, cell lysates or other biological fluids.

Tissue Specificity
Post Translational Modifications	Undergoes autophagy-mediated degradation in the liver in a time-dependent manner.
Function	Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA. SCF(BTRC) directs ubiquitination of NFKBIB, NFKBIE, ATF4, SMAD3, SMAD4, CDC25A, FBXO5, CEP68 and probably NFKB2. SCF(SKP2) directs ubiquitination of phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition. SCF(SKP2) directs ubiquitination of ORC1, CDT1, RBL2, ELF4, CDKN1A, RAG2, FOXO1A, and probably MYC and TAL1. SCF(FBXW7) directs ubiquitination of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1. SCF(FBXW2) directs ubiquitination of GCM1. SCF(FBXO32) directs ubiquitination of MYOD1. SCF(FBXO7) directs ubiquitination of BIRC2 and DLGAP5. SCF(FBXO33) directs ubiquitination of YBX1. SCF(FBXO11) directs ubiquitination of BCL6 and DTL but does not seem to direct ubiquitination of TP53. SCF(BTRC) mediates the ubiquitination of NFKBIA at 'Lys-21' and 'Lys-22'.the degradation frees the associated NFKB1-RELA dimer to translocate into the nucleus and to activate transcription. SCF(CCNF) directs ubiquitination of CCP110. SCF(FBXL3) and SCF(FBXL21) direct ubiquitination of CRY1 and CRY2. SCF(FBXO9) directs ubiquitination of TTI1 and TELO2. SCF(FBXO10) directs ubiquitination of BCL2.
Protein Name	S-Phase Kinase-Associated Protein 1 Cyclin-A/Cdk2-Associated Protein P19 P19a Organ Of Corti Protein 2 Ocp-2 Organ Of Corti Protein Ii Ocp-Ii Rna Polymerase Ii Elongation Factor-Like Protein Siii Transcription Elongation Factor B Polypeptide 1-Like P19skp1
Database Links	Reactome: R-HSA-1169091 Reactome: R-HSA-1170546 Reactome: R-HSA-174113 Reactome: R-HSA-180534 Reactome: R-HSA-187577 Reactome: R-HSA-195253 Reactome: R-HSA-202424 Reactome: R-HSA-2122947 Reactome: R-HSA-2565942 Reactome: R-HSA-2644606 Reactome: R-HSA-2644607 Reactome: R-HSA-2871837 Reactome: R-HSA-2894862 Reactome: R-HSA-400253 Reactome: R-HSA-5607761 Reactome: R-HSA-5607764 Reactome: R-HSA-5610780 Reactome: R-HSA-5610783 Reactome: R-HSA-5610785 Reactome: R-HSA-5676590 Reactome: R-HSA-5684264 Reactome: R-HSA-68949 Reactome: R-HSA-69231 Reactome: R-HSA-8854050 Reactome: R-HSA-8939902 Reactome: R-HSA-8951664 Reactome: R-HSA-9020702 Reactome: R-HSA-917937 Reactome: R-HSA-9604323 Reactome: R-HSA-9708530 Reactome: R-HSA-9725371 Reactome: R-HSA-9762114 Reactome: R-HSA-983168
Cellular Localisation
Alternative ELISA Names	S-Phase Kinase-Associated Protein 1 ELISA kit Cyclin-A/Cdk2-Associated Protein P19 ELISA kit P19a ELISA kit Organ Of Corti Protein 2 ELISA kit Ocp-2 ELISA kit Organ Of Corti Protein Ii ELISA kit Ocp-Ii ELISA kit Rna Polymerase Ii Elongation Factor-Like Protein ELISA kit Siii ELISA kit Transcription Elongation Factor B Polypeptide 1-Like ELISA kit P19skp1 ELISA kit SKP1 ELISA kit EMC19 ELISA kit OCP2 ELISA kit SKP1A ELISA kit TCEB1L ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

温馨提示：为规避购买风险，建议您在购买前务必确认供应商资质与产品质量。
免责申明：以上内容为注册会员自行发布，若信息的真实性、合法性存在争议，平台将会监督协助处理，欢迎举报

产品目录

产品资料

Human SKP1 (S-Phase Kinase Associated Protein 1) Sandwich ELISA Kit Ready-To-Use (STJE0018569)