Anti-CHRNA7 antibody (STJA0010232) STJA0010232 上海玉博生物科技有限公司

Anti-CHRNA7 antibody (STJA0010232)

简单介绍

Anti-CHRNA7 antibody (STJA0010232)

产品描述

Host:	Rabbit
Applications:	WB/ELISA
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Neuronal acetylcholine receptor subunit alpha-7 is suitable for use in Western Blot and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:1000-2000 ELISA 1:5000-20000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CHRNA7
Gene ID:	1139/89832
Uniprot ID:	ACHA7_HUMAN
Specificity:	This antibody detects endogenous levels of Human, Mouse, Rat AChR Alpha 7
Immunogen:	Synthesized peptide derived from human AChR Alpha 7

Post Translational Modifications	Glycosylations at Asn-46, Asn-90 and Asn-133 are essential for TMEM35A/NACHO-mediated proper subunit assembly and trafficking to the cell membrane.
Function	After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.
Protein Name	Neuronal Acetylcholine Receptor Subunit Alpha-7
Database Links	Reactome: R-HSA-629594
Cellular Localisation	Postsynaptic Cell Membrane Multi-Pass Membrane Protein Cell Membrane Tmem35a/Nacho Promotes Its Trafficking To The Cell Membrane Ric3 Promotes Its Trafficking To The Cell Membrane
Alternative Antibody Names	Anti-Neuronal Acetylcholine Receptor Subunit Alpha-7 antibody Anti-CHRNA7 antibody Anti-NACHRA7 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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