Anti-CHRNA9 antibody (26-240) (STJ112016) STJ112016 上海玉博生物科技有限公司

Anti-CHRNA9 antibody (26-240) (STJ112016)

简单介绍

Anti-CHRNA9 antibody (26-240) (STJ112016)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CHRNA9 (26-240) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:1000-1:4000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CHRNA9
Gene ID:	55584
Uniprot ID:	ACHA9_HUMAN
Immunogen Region:	26-240
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 26-240 of human CHRNA9 (NP_060051.2).
Immunogen Sequence:	ADGKYAQKLFNDLFEDYSNA LRPVEDTDKVLNVTLQITLS QIKDMDERNQILTAYLWIRQ IWHDAYLTWDRDQYDGLDSI RIPSDLVWRPDIVLYNKADD ESSEPVNTNVVLRYDGLITW DAPAITKSSCVVDVTYFPFD NQQCNLTFGSWTYNGNQVDI FNALDSGDLSDFIEDVEWEV HGMPAVKNVISYGCCSEPYP DVTFTLLLKRRSSFY

Tissue Specificity	Expressed in cochlea, keratinocytes, pituitary gland, B-cells and T-cells.
Post Translational Modifications	N-glycosylated.
Function	Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding induces a conformation change that leads to the opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. May also regulate keratinocyte adhesion.
Protein Name	Neuronal Acetylcholine Receptor Subunit Alpha-9 Nicotinic Acetylcholine Receptor Subunit Alpha-9 Nachr Alpha-9
Database Links	Reactome: R-HSA-629594 Reactome: R-HSA-9667769
Cellular Localisation	Postsynaptic Cell Membrane Multi-Pass Membrane Protein Cell Membrane
Alternative Antibody Names	Anti-Neuronal Acetylcholine Receptor Subunit Alpha-9 antibody Anti-Nicotinic Acetylcholine Receptor Subunit Alpha-9 antibody Anti-Nachr Alpha-9 antibody Anti-CHRNA9 antibody Anti-NACHRA9 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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