Anti-Cathepsin B antibody (Internal) (STJ73733) STJ73733-100 上海玉博生物科技有限公司

Anti-Cathepsin B antibody (Internal) (STJ73733)

简单介绍

Anti-Cathepsin B antibody (Internal) (STJ73733)

产品描述

Host:	Goat
Applications:	Pep-ELISA/WB/IF/IHC/FC
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Goat polyclonal antibody anti-Cathepsin B (Internal) is suitable for use in ELISA, Western Blot, Immunofluorescence, Immunohistochemistry and Flow Cytometry research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	0.5 mg/mL
Dilution Range:	WB-0.5-2µg/ml IHC-5µg/ml IF-Strong expression of the protein seen in the cytoplasm/vesicles of HeLa cells. 10µg/ml ELISA-antibody detection limit dilution 1:64000.
Storage Instruction:	Store at-20°C on receipt and minimise freeze-thaw cycles.

Gene Symbol:	CTSB
Gene ID:	1508
Uniprot ID:	CATB_HUMAN
Immunogen Region:	Internal
Accession Number:	NP_001899.1
Specificity:	Reported variants represent identical protein: NP_680091.1, NP_680090.1, NP_680092.1, NP_001899.1, NP_680093.1.
Immunogen Sequence:	SDRICIHTNAHVSVE

Function	Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Cleaves matrix extracellular phosphoglycoprotein MEPE. Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen. Has also been implicated in tumor invasion and metastasis.
Protein Name	Cathepsin B App Secretase Apps Cathepsin B1 Cleaved Into - Cathepsin B Light Chain - Cathepsin B Heavy Chain
Database Links	Reactome: R-HSA-1442490 Reactome: R-HSA-1679131 Reactome: R-HSA-2022090 Reactome: R-HSA-2132295 Reactome: R-HSA-6798695
Cellular Localisation	Lysosome Melanosome Secreted Extracellular Space Apical Cell Membrane Peripheral Membrane Protein Extracellular Side Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv Localizes To The Lumen Of Thyroid Follicles And To The Apical Membrane Of Thyroid Epithelial Cells
Alternative Antibody Names	Anti-Cathepsin B antibody Anti-App Secretase antibody Anti-Apps antibody Anti-Cathepsin B1 Cleaved Into - Cathepsin B Light Chain - Cathepsin B Heavy Chain antibody Anti-CTSB antibody Anti-CPSB antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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