Anti-cathepsin C/DPP1 antibody (238-252) (STJ72905) STJ72905-100 上海玉博生物科技有限公司

Anti-cathepsin C/DPP1 antibody (238-252) (STJ72905)

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产品名称：Anti-cathepsin C/DPP1 antibody (238-252) (STJ72905)
产品型号：STJ72905-100
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-cathepsin C/DPP1 antibody (238-252) (STJ72905)

产品描述

Host:	Goat
Applications:	Pep-ELISA/WB/IHC
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Goat polyclonal antibody anti-cathepsin C/DPP1 (238-252) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	0.5 mg/mL
Dilution Range:	WB-1-3µg/ml IHC-5µg/ml ELISA-antibody detection limit dilution 1:128000.
Storage Instruction:	Store at-20°C on receipt and minimise freeze-thaw cycles.

Gene Symbol:	CTSC
Gene ID:	1075
Uniprot ID:	CATC_HUMAN
Immunogen Region:	238-252
Accession Number:	NP_001805.3
Specificity:	This antibody is expected to recognize isoform a (NP_001805.3) only.
Immunogen Sequence:	RNVHGINFVSPVRNQ

Post Translational Modifications	N-glycosylated. While glycosylation at Asn-53, Asn-119 and Asn-276 is mediated by STT3A-containing complexes, glycosylation at Asn-29 is mediated STT3B-containing complexes. In approximately 50% of the complexes the exclusion domain is cleaved at position 58 or 61. The two parts of the exclusion domain are held together by a disulfide bond.
Function	Thiol protease. Has dipeptidylpeptidase activity. Active against a broad range of dipeptide substrates composed of both polar and hydrophobic amino acids. Proline cannot occupy the P1 position and arginine cannot occupy the P2 position of the substrate. Can act as both an exopeptidase and endopeptidase. Activates serine proteases such as elastase, cathepsin G and granzymes A and B.
Protein Name	Dipeptidyl Peptidase 1 Cathepsin C Cathepsin J Dipeptidyl Peptidase I Dpp-I Dppi Dipeptidyl Transferase Cleaved Into - Dipeptidyl Peptidase 1 Exclusion Domain Chain Dipeptidyl Peptidase I Exclusion Domain Chain - Dipeptidyl Peptidase 1 Heavy Chain Dipeptidyl Peptidase I Heavy Chain - Dipeptidyl Peptidase 1 Light Chain Dipeptidyl Peptidase I Light Chain
Database Links	Reactome: R-HSA-204005 Reactome: R-HSA-2132295 Reactome: R-HSA-5694530 Reactome: R-HSA-6798695
Cellular Localisation	Lysosome
Alternative Antibody Names	Anti-Dipeptidyl Peptidase 1 antibody Anti-Cathepsin C antibody Anti-Cathepsin J antibody Anti-Dipeptidyl Peptidase I antibody Anti-Dpp-I antibody Anti-Dppi antibody Anti-Dipeptidyl Transferase Cleaved Into - Dipeptidyl Peptidase 1 Exclusion Domain Chain antibody Anti-Dipeptidyl Peptidase I Exclusion Domain Chain - Dipeptidyl Peptidase 1 Heavy Chain antibody Anti-Dipeptidyl Peptidase I Heavy Chain - Dipeptidyl Peptidase 1 Light Chain antibody Anti-Dipeptidyl Peptidase I Light Chain antibody Anti-CTSC antibody Anti-CPPI antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-cathepsin C/DPP1 antibody (238-252) (STJ72905)