Anti-CAVIN2 antibody (325-425) (STJ11105248) STJ11105248 上海玉博生物科技有限公司

Anti-CAVIN2 antibody (325-425) (STJ11105248)

简单介绍

Anti-CAVIN2 antibody (325-425) (STJ11105248)

产品描述

Host:	Rabbit
Applications:	WB/IHC
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Caveolae-Associated Protein 2 (325-425) is suitable for use in Western Blot and Immunohistochemistry research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:1000 IHC-P 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CAVIN2
Gene ID:	8436
Uniprot ID:	CAVN2_HUMAN
Immunogen Region:	325-425
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 325-425 of human CAVIN2 (NP_004648.1).
Immunogen Sequence:	PNDQEEESFAEGHSEASLAS ALVEGEIAEEAAEKATSRGS NSGMDSNIDLTIVEDEEEES VALEQAQKVRYEGSYALTSE EAERSDGDPVQPAVLQVHQT S

Tissue Specificity	Highly expressed in heart and lung, and expressed at lower levels in brain, kidney, liver, pancreas, placenta, and skeletal muscle.
Post Translational Modifications	Phosphorylated on Ser residues.
Function	Plays an important role in caveolar biogenesis and morphology. Regulates caveolae morphology by inducing membrane curvature within caveolae. Plays a role in caveola formation in a tissue-specific manner. Required for the formation of caveolae in the lung and fat endothelia but not in the heart endothelia. Negatively regulates the size or stability of CAVIN complexes in the lung endothelial cells. May play a role in targeting PRKCA to caveolae.
Protein Name	Caveolae-Associated Protein 2 Cavin-2 Ps-P68 Phosphatidylserine-Binding Protein Serum Deprivation-Response Protein
Cellular Localisation	Cytoplasm Cytosol Membrane Caveola Localizes In The Caveolae In A Caveolin-Dependent Manner
Alternative Antibody Names	Anti-Caveolae-Associated Protein 2 antibody Anti-Cavin-2 antibody Anti-Ps-P68 antibody Anti-Phosphatidylserine-Binding Protein antibody Anti-Serum Deprivation-Response Protein antibody Anti-CAVIN2 antibody Anti-SDPR antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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