Human SNX9 (Sorting Nexin 9) Sandwich ELISA Kit (STJE0012255) STJE0012255 上海玉博生物科技有限公司

Human SNX9 (Sorting Nexin 9) Sandwich ELISA Kit (STJE0012255)

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产品名称：Human SNX9 (Sorting Nexin 9) Sandwich ELISA Kit (STJE0012255)
产品型号：STJE0012255
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human SNX9 (Sorting Nexin 9) Sandwich ELISA Kit (STJE0012255)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.052ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This SNX9 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	SNX9
Gene ID:	51429
Uniprot ID:	SNX9_HUMAN
Sample Type:	serum, plasma, tissue homogenates or other biological fluids.

Tissue Specificity	Widely expressed, with highest levels in heart and placenta, and lowest levels in thymus and peripheral blood leukocytes.
Post Translational Modifications	Ubiquitinated by ITCH. Phosphorylated on tyrosine residues by TNK2. Phosphorylation promotes its activity in the degradation of EGFR.
Function	Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Promotes internalization of TNFR. Promotes degradation of EGFR after EGF signaling. Stimulates the GTPase activity of DNM1. Promotes DNM1 oligomerization. Promotes activation of the Arp2/3 complex by WASL, and thereby plays a role in the reorganization of the F-actin cytoskeleton. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Has lower affinity for membranes enriched in phosphatidylinositol 3-phosphate.
Protein Name	Sorting Nexin-9 Sh3 And Px Domain-Containing Protein 1 Protein Sdp1 Sh3 And Px Domain-Containing Protein 3a
Database Links	Reactome: R-HSA-432722 Reactome: R-HSA-8856828
Cellular Localisation	Cytoplasmic Vesicle Membrane Peripheral Membrane Protein Cytoplasmic Side Cell Membrane Cytoplasmic Vesicle Clathrin-Coated Vesicle Golgi Apparatus Trans-Golgi Network Cell Projection Ruffle Cytoplasm Localized At Sites Of Endocytosis At The Cell Membrane Detected On Newly Formed Macropinosomes Transiently Recruited To Clathrin-Coated Pits At A Late Stage Of Clathrin-Coated Vesicle Formation Colocalizes With The Actin Cytoskeleton At The Cell Membrane
Alternative ELISA Names	Sorting Nexin-9 ELISA kit Sh3 And Px Domain-Containing Protein 1 ELISA kit Protein Sdp1 ELISA kit Sh3 And Px Domain-Containing Protein 3a ELISA kit SNX9 ELISA kit SH3PX1 ELISA kit SH3PXD3A ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Human SNX9 (Sorting Nexin 9) Sandwich ELISA Kit (STJE0012255)