Anti-CHST1 antibody (Internal) (STJ92283) STJ92283 上海玉博生物科技有限公司

Anti-CHST1 antibody (Internal) (STJ92283)

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产品名称：Anti-CHST1 antibody (Internal) (STJ92283)
产品型号：STJ92283
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-CHST1 antibody (Internal) (STJ92283)

产品描述

Host:	Rabbit
Applications:	WB/ELISA
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Carbohydrate sulfotransferase 1 (Internal) is suitable for use in Western Blot and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 ELISA 1:10000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CHST1
Gene ID:	8534
Uniprot ID:	CHST1_HUMAN
Immunogen Region:	Internal
Specificity:	CHST1 Polyclonal Antibody detects endogenous levels of CHST1 protein.
Immunogen:	Synthesized peptide derived from the Internal region of human CHST1.

Function	Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of internal galactose (Gal) residues of keratan. Cooperates with B4GALT4 and B3GNT7 glycosyltransferases and CHST6 sulfotransferase to construct and elongate disulfated disaccharide unit ->3(6-sulfoGalbeta)1->4(6-sulfoGlcNAcbeta)1-> within keratan sulfate polymer. Has a preference for sulfating keratan sulfate, but it also transfers sulfate to the unsulfated polymer. Involved in biosynthesis of phosphacan, a major keratan sulfate proteoglycan in the developing brain. Involved in biosynthesis of 6-sulfoGalbeta-containing O-linked glycans in high endothelial venules of lymph nodes. May act in a synergistic manner with CHST4 to generate sialyl 6',6-disulfo Lewis X motif, a recognition determinant for immune cell receptors implicated in leukocyte trafficking. Catalyzes sulfation of N-acetyllactosamine (LacNAc) oligosaccharides with highest efficiency for sialylated LacNAc structures.
Protein Name	Carbohydrate Sulfotransferase 1 Galactose/N-Acetylglucosamine/N-Acetylglucosamine 6-O-Sulfotransferase 1 Gst-1 Keratan Sulfate Gal-6 Sulfotransferase Ks6st Ksgal6st Ksst
Database Links	Reactome: R-HSA-2022854
Cellular Localisation	Golgi Apparatus Membrane Single-Pass Type Ii Membrane Protein
Alternative Antibody Names	Anti-Carbohydrate Sulfotransferase 1 antibody Anti-Galactose/N-Acetylglucosamine/N-Acetylglucosamine 6-O-Sulfotransferase 1 antibody Anti-Gst-1 antibody Anti-Keratan Sulfate Gal-6 Sulfotransferase antibody Anti-Ks6st antibody Anti-Ksgal6st antibody Anti-Ksst antibody Anti-CHST1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-CHST1 antibody (Internal) (STJ92283)