Anti-CHST2 antibody (231-530) (STJ118200) STJ118200 上海玉博生物科技有限公司

Anti-CHST2 antibody (231-530) (STJ118200)

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产品名称：Anti-CHST2 antibody (231-530) (STJ118200)
产品型号：STJ118200
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-CHST2 antibody (231-530) (STJ118200)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CHST2 (231-530) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CHST2
Gene ID:	9435
Uniprot ID:	CHST2_HUMAN
Immunogen Region:	231-530
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 231-530 of human CHST2 (NP_004258.2).
Immunogen Sequence:	FQLYSPAGSGGRNLTTLGIF GAATNKVVCSSPLCPAYRKE VVGLVDDRVCKKCPPQRLAR FEEECRKYRTLVIKGVRVFD VAVLAPLLRDPALDLKVIHL VRDPRAVASSRIRSRHGLIR ESLQVVRSRDPRAHRMPFLE AAGHKLGAKKEGVGGPADYH ALGAMEVICNSMAKTLQTAL QPPDWLQGHYLVVRYEDLVG DPVKTLRRVYDFVGLLVSPE MEQFALNMTSGSGSSSKPF

Tissue Specificity	Widely expressed. Highly expressed in bone marrow, peripheral blood leukocytes, spleen, brain, spinal cord, ovary and placenta. Expressed by high endothelial cells (HEVs) and leukocytes.
Post Translational Modifications	Glycosylation at Asn-475 is required for catalytic activity.
Function	Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues within keratan-like structures on N-linked glycans and within mucin-associated glycans that can ultimately serve as SELL ligands. SELL ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. Participates in biosynthesis of the SELL ligand sialyl 6-sulfo Lewis X and in lymphocyte homing to Peyer patches. Has no activity toward O-linked sugars. Its substrate specificity may be influenced by its subcellular location. Sulfates GlcNAc residues at terminal, non-reducing ends of oligosaccharide chains.
Protein Name	Carbohydrate Sulfotransferase 2 Galactose/N-Acetylglucosamine/N-Acetylglucosamine 6-O-Sulfotransferase 2 Gst-2 N-Acetylglucosamine 6-O-Sulfotransferase 1 Glcnac6st-1 Gn6st-1
Database Links	Reactome: R-HSA-2022854
Cellular Localisation	Golgi Apparatus Trans-Golgi Network Membrane Single-Pass Type Ii Membrane Protein
Alternative Antibody Names	Anti-Carbohydrate Sulfotransferase 2 antibody Anti-Galactose/N-Acetylglucosamine/N-Acetylglucosamine 6-O-Sulfotransferase 2 antibody Anti-Gst-2 antibody Anti-N-Acetylglucosamine 6-O-Sulfotransferase 1 antibody Anti-Glcnac6st-1 antibody Anti-Gn6st-1 antibody Anti-CHST2 antibody Anti-GN6ST antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-CHST2 antibody (231-530) (STJ118200)