Anti-CHTF18 antibody (794-975) (STJ119791) STJ119791 上海玉博生物科技有限公司

Anti-CHTF18 antibody (794-975) (STJ119791)

简单介绍

Anti-CHTF18 antibody (794-975) (STJ119791)

产品描述

Host:	Rabbit
Applications:	WB/IF
Reactivity:	Human/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CHTF18 (794-975) is suitable for use in Western Blot and Immunofluorescence research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000 IF/ICC 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CHTF18
Gene ID:	63922
Uniprot ID:	CTF18_HUMAN
Immunogen Region:	794-975
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 794-975 of human CHTF18 (NP_071375.1).
Immunogen Sequence:	GTMLAYSLTYRQERTPDGQY IYRLEPNVEELCRFPELPAR KPLTYQTKQLIAREIEVEKM RRAEASARVENSPQVDGSPP GLEGLLGGIGEKGVHRPAPR NHEQRLEHIMRRAAREEQPE KDFFGRVVVRSTAVPSAGDT APEQDSVERRMGTAVGRSEV WFRFNEGVSNAVRRSLYIRD LL

Function	Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated by the presence of primed DNA, replication protein A (RPA) and by proliferating cell nuclear antigen (PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loading of PCNA onto primed and gapped DNA. Interacts with and stimulates DNA polymerase POLH. During DNA repair synthesis, involved in loading DNA polymerase POLE at the sites of local damage.
Protein Name	Chromosome Transmission Fidelity Protein 18 Homolog Hctf18 Chl12
Database Links	Reactome: R-HSA-174411
Cellular Localisation	Nucleus Associates With Chromatin During S Phase
Alternative Antibody Names	Anti-Chromosome Transmission Fidelity Protein 18 Homolog antibody Anti-Hctf18 antibody Anti-Chl12 antibody Anti-CHTF18 antibody Anti-C16orf41 antibody Anti-CTF18 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

产品目录