Anti-CIAO1 antibody (1-339) (STJ29494) STJ29494 上海玉博生物科技有限公司

Anti-CIAO1 antibody (1-339) (STJ29494)

简单介绍

Anti-CIAO1 antibody (1-339) (STJ29494)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CIAO1 (1-339) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CIAO1
Gene ID:	9391
Uniprot ID:	CIAO1_HUMAN
Immunogen Region:	1-339
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-339 of human CIAO1 (NP_004795.1).
Immunogen Sequence:	MKDSLVLLGRVPAHPDSRCW FLAWNPAGTLLASCGGDRRI RIWGTEGDSWICKSVLSEGH QRTVRKVAWSPCGNYLASAS FDATTCIWKKNQDDFECVTT LEGHENEVKSVAWAPSGNLL ATCSRDKSVWVWEVDEEDEY ECVSVLNSHTQDVKHVVWHP SQELLASASYDDTVKLYREE EDDWVCCATLEGHESTVWSL AFDPSGQRLASCSDDRTVRI WRQYLPGNEQGVACSGSDP

Function	Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors. The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. CIAO1:CIAO2A specifically matures ACO1 and stabilizes IREB2. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.
Protein Name	Probable Cytosolic Iron-Sulfur Protein Assembly Protein Ciao1 Wd Repeat-Containing Protein 39
Database Links	Reactome: R-HSA-2564830
Cellular Localisation	Cytoplasm
Alternative Antibody Names	Anti-Probable Cytosolic Iron-Sulfur Protein Assembly Protein Ciao1 antibody Anti-Wd Repeat-Containing Protein 39 antibody Anti-CIAO1 antibody Anti-CIA1 antibody Anti-WDR39 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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