Anti-CIDEA antibody (140-220 aa) (STJ190406) STJ190406 上海玉博生物科技有限公司

Anti-CIDEA antibody (140-220 aa) (STJ190406)

简单介绍

Anti-CIDEA antibody (140-220 aa) (STJ190406)

产品描述

Host:	Rabbit
Applications:	WB/ELISA
Reactivity:	Human/Rat/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Lipid transferase CIDEA (140-220 aa) is suitable for use in Western Blot and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-2000 ELISA 1:5000-20000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CIDEA
Gene ID:	1149
Uniprot ID:	CIDEA_HUMAN
Immunogen Region:	140-220 aa
Specificity:	CIDEA Polyclonal Antibody detects endogenous levels of protein.
Immunogen:	Synthesized peptide derived from the human protein at the amino acid range 140-220

Function	Lipid transferase that promotes unilocular lipid droplet formation by mediating lipid droplet fusion. Lipid droplet fusion promotes their enlargement, restricting lipolysis and favoring lipid storage. Localizes on the lipid droplet surface, at focal contact sites between lipid droplets, and mediates atypical lipid droplet fusion by promoting directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair and occurs at a lower rate than that promoted by CIDEC. May also act as a CEBPB coactivator in epithelial cells to control the expression of a subset of CEBPB downstream target genes, including ID2, IGF1, PRLR, SOCS1, SOCS3, XDH, but not casein. By interacting with CEBPB, strengthens the association of CEBPB with the XDH promoter, increases histone acetylation and dissociates HDAC1 from the promoter. When overexpressed, induces apoptosis.the physiological significance of its role in apoptosis is unclear.
Protein Name	Lipid Transferase Cidea Cell Death Activator Cide-A Cell Death-Inducing Dffa-Like Effector A
Database Links	Reactome: R-HSA-8964572
Cellular Localisation	Lipid Droplet Nucleus Enriched At Lipid Droplet Contact Sites
Alternative Antibody Names	Anti-Lipid Transferase Cidea antibody Anti-Cell Death Activator Cide-A antibody Anti-Cell Death-Inducing Dffa-Like Effector A antibody Anti-CIDEA antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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