Anti-CIRH1A antibody (497-686) (STJ111325) STJ111325 上海玉博生物科技有限公司

Anti-CIRH1A antibody (497-686) (STJ111325)

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产品名称：Anti-CIRH1A antibody (497-686) (STJ111325)
产品型号：STJ111325
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-CIRH1A antibody (497-686) (STJ111325)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CIRH1A (497-686) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	UTP4
Gene ID:	84916
Uniprot ID:	UTP4_HUMAN
Immunogen Region:	497-686
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 497-686 of human CIRH1A (NP_116219.2).
Immunogen Sequence:	NWLAASGTSAGVHVYNVKQL KLHCTVPAYNFPVTAMAIAP NTNNLVIAHSDQQVFEYSIP DKQYTDWSRTVQKQGFHHLW LQRDTPITHISFHPKRPMHI LLHDAYMFCIIDKSLPLPND KTLLYNPFPPTNESDVIRRR TAHAFKISKIYKPLLFMDLL DERTLVAVERPLDDIIAQLP PPIKKKKFGT

Post Translational Modifications	May be phosphorylated during mitosis.may control the association of this protein with WRD43 and UTP15.
Function	Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted d Involved in SSU pre-rRNA processing at sites A', A0, 1 and 2b. Required for optimal pre-ribosomal RNA transcription by RNA polymerase. May be a transcriptional regulator. (Microbial infection) Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5'-GGGACTTTCC-3' found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV.
Protein Name	U3 Small Nucleolar Rna-Associated Protein 4 Homolog Cirhin Utp4 Small Subunit Processome Component
Database Links	Reactome: R-HSA-6790901 Reactome: R-HSA-6791226
Cellular Localisation	Nucleus Nucleolus Chromosome Found Predominantly At The Fibrillar Center
Alternative Antibody Names	Anti-U3 Small Nucleolar Rna-Associated Protein 4 Homolog antibody Anti-Cirhin antibody Anti-Utp4 Small Subunit Processome Component antibody Anti-UTP4 antibody Anti-CIRH1A antibody Anti-cPERP-E antibody Anti-KIAA1988 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-CIRH1A antibody (497-686) (STJ111325)