Anti-CITED2 antibody (1-100) (STJ11105425) STJ11105425 上海玉博生物科技有限公司

Anti-CITED2 antibody (1-100) (STJ11105425)

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产品名称：Anti-CITED2 antibody (1-100) (STJ11105425)
产品型号：STJ11105425
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-CITED2 antibody (1-100) (STJ11105425)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Cbp/P300-Interacting Transactivator 2 (1-100) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:1000-1:5000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CITED2
Gene ID:	10370
Uniprot ID:	CITE2_HUMAN
Immunogen Region:	1-100
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CITED2 (NP_001161860.1).
Immunogen Sequence:	MADHMMAMNHGRFPDGTNGL HHHPAHRMGMGQFPSPHHHQ QQQPQHAFNALMGEHIHYGA GNMNATSGIRHAMGPGTVNG GHPPSALAPAARFNNSQFMG

Function	Transcriptional coactivator of the p300/CBP-mediated transcription complex. Acts as a bridge, linking TFAP2 transcription factors and the p300/CBP transcriptional coactivator complex in order to stimulate TFAP2-mediated transcriptional activation. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Stimulates the peroxisome proliferator-activated receptors PPARA transcriptional activity. Enhances estrogen-dependent transactivation mediated by estrogen receptors. Acts also as a transcriptional corepressor.interferes with the binding of the transcription factors HIF1A or STAT2 and the p300/CBP transcriptional coactivator complex. Participates in sex determination and early gonad development by stimulating transcription activation of SRY. Plays a role in controlling left-right patterning during embryogenesis.potentiates transcriptional activation of NODAL-mediated gene transcription in the left lateral plate mesoderm (LPM). Plays an essential role in differentiation of the adrenal cortex from the adrenogonadal primordium (AGP).stimulates WT1-mediated transcription activation thereby up-regulating the nuclear hormone receptor NR5A1 promoter activity. Associates with chromatin to the PITX2 P1 promoter region.
Protein Name	Cbp/P300-Interacting Transactivator 2 Msg-Related Protein 1 Mrg-1 P35srj
Database Links	Reactome: R-HSA-1234158 Reactome: R-HSA-8866906 Reactome: R-HSA-8866907 Reactome: R-HSA-9614657
Cellular Localisation	Nucleus Colocalizes With Ep300 In Dot-Like Structures
Alternative Antibody Names	Anti-Cbp/P300-Interacting Transactivator 2 antibody Anti-Msg-Related Protein 1 antibody Anti-Mrg-1 antibody Anti-P35srj antibody Anti-CITED2 antibody Anti-MRG1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-CITED2 antibody (1-100) (STJ11105425)