Anti-CKB antibody (182-381) (STJ114505) STJ114505 上海玉博生物科技有限公司

Anti-CKB antibody (182-381) (STJ114505)

简单介绍

Anti-CKB antibody (182-381) (STJ114505)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CKB (182-381) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:1000-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CKB
Gene ID:	1152
Uniprot ID:	KCRB_HUMAN
Immunogen Region:	182-381
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 182-381 of human Creatine kinase B type (Creatine kinase B type (CKB) ) (NP_001814.2).
Immunogen Sequence:	AEQQQLIDDHFLFDKPVSPL LLASGMARDWPDARGIWHND NKTFLVWVNEEDHLRVISMQ KGGNMKEVFTRFCTGLTQIE TLFKSKDYEFMWNPHLGYIL TCPSNLGTGLRAGVHIKLPN LGKHEKFSEVLKRLRLQKRG TGGVDTAAVGGVFDVSNADR LGFSEVELVQMVVDGVKLLI EMEQRLEQGQAIDDLMPAQK

Function	Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa (Probable). Acts as a key regulator of adaptive thermogenesis as part of the futile creatine cycle: localizes to the mitochondria of thermogenic fat cells and acts by mediating phosphorylation of creatine to initiate a futile cycle of creatine phosphorylation and dephosphorylation. During the futile creatine cycle, creatine and N-phosphocreatine are in a futile cycle, which dissipates the high energy charge of N-phosphocreatine as heat without performing any mechanical or chemical work.
Protein Name	Creatine Kinase B-Type Brain Creatine Kinase B-Ck Creatine Kinase B Chain Creatine Phosphokinase B-Type Cpk-B
Database Links	Reactome: R-HSA-71288 Reactome: R-HSA-9696264
Cellular Localisation	Cytoplasm Cytosol Mitochondrion Cell Membrane Localizes To The Mitochondria Of Thermogenic Fat Cells Via The Internal Mts-Like Signal (Imts-L) Region
Alternative Antibody Names	Anti-Creatine Kinase B-Type antibody Anti-Brain Creatine Kinase antibody Anti-B-Ck antibody Anti-Creatine Kinase B Chain antibody Anti-Creatine Phosphokinase B-Type antibody Anti-Cpk-B antibody Anti-CKB antibody Anti-CKBB antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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