Anti-CLCA1 antibody (22-150) (STJ117235) STJ117235 上海玉博生物科技有限公司

Anti-CLCA1 antibody (22-150) (STJ117235)

如果您对该产品感兴趣的话，可以
产品名称：Anti-CLCA1 antibody (22-150) (STJ117235)
产品型号：STJ117235
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-CLCA1 antibody (22-150) (STJ117235)

产品描述

Host:	Rabbit
Applications:	WB/IF
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CLCA1 (22-150) is suitable for use in Western Blot and Immunofluorescence research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000 IF/ICC 1:50-1:100
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CLCA1
Gene ID:	1179
Uniprot ID:	CLCA1_HUMAN
Immunogen Region:	22-150
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 22-150 of human CLCA1 (NP_001276.2).
Immunogen Sequence:	NSLIQLNNNGYEGIVVAIDP NVPEDETLIQQIKDMVTQAS LYLFEATGKRFYFKNVAILI PETWKTKADYVRPKLETYKN ADVLVAESTPPGNDEPYTEQ MGNCGEKGERIHLTPDFIAG KKLAEYGPQ

Tissue Specificity	Highly expressed in small intestine and colon namely in intestinal basal crypt epithelia and goblet cells, and appendix. Weakly expressed in uterus, testis and kidney. Expressed in the airways epithelium of both asthmatic and healthy patients. Expressed in the bronchial epithelium, especially in mucus-producing goblet cells. Expressed in normal turbinate mucosa and nasal polyp. Expressed in.
Post Translational Modifications	Glycosylated. The 125-kDa product is autoproteolytically processed by the metalloprotease domain and yields to two cell-surface-associated subunits, a 90-kDa protein and a group of 37- to 41-kDa proteins. The cleavage is necessary for calcium-activated chloride channel (CaCC) activation activity.
Function	May be involved in mediating calcium-activated chloride conductance. May play critical roles in goblet cell metaplasia, mucus hypersecretion, cystic fibrosis and AHR. May be involved in the regulation of mucus production and/or secretion by goblet cells. Involved in the regulation of tissue inflammation in the innate immune response. May play a role as a tumor suppressor. Induces MUC5AC.
Protein Name	Calcium-Activated Chloride Channel Regulator 1 Calcium-Activated Chloride Channel Family Member 1 Hclca1 Calcium-Activated Chloride Channel Protein 1 Cacc-1 Hcacc-1
Database Links	Reactome: R-HSA-2672351
Cellular Localisation	Secreted Extracellular Space Cell Membrane Peripheral Membrane Protein Extracellular Side Protein That Remains Attached To The Plasma Membrane Appeared To Be Predominantly Localized To Microvilli
Alternative Antibody Names	Anti-Calcium-Activated Chloride Channel Regulator 1 antibody Anti-Calcium-Activated Chloride Channel Family Member 1 antibody Anti-Hclca1 antibody Anti-Calcium-Activated Chloride Channel Protein 1 antibody Anti-Cacc-1 antibody Anti-Hcacc-1 antibody Anti-CLCA1 antibody Anti-CACC1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

温馨提示：为规避购买风险，建议您在购买前务必确认供应商资质与产品质量。
免责申明：以上内容为注册会员自行发布，若信息的真实性、合法性存在争议，平台将会监督协助处理，欢迎举报

产品目录

产品资料

Anti-CLCA1 antibody (22-150) (STJ117235)