Anti-CC2D1A antibody (STJ191919) STJ191919 上海玉博生物科技有限公司

Anti-CC2D1A antibody (STJ191919)

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产品名称：Anti-CC2D1A antibody (STJ191919)
产品型号：STJ191919
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-CC2D1A antibody (STJ191919)

产品描述

Host:	Rabbit
Applications:	WB/ELISA
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Coiled-coil and C2 domain-containing protein 1A is suitable for use in Western Blot and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-2000 ELISA 1:5000-20000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CC2D1A
Gene ID:	54862
Uniprot ID:	C2D1A_HUMAN
Specificity:	C2D1A Polyclonal Antibody detects endogenous levels of protein.
Immunogen:	Synthesized peptide derived from part of the human protein

Function	Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses. Plays distinct roles depending on its localization. When cytoplasmic, acts as a scaffold protein in the PI3K/PDK1/AKT pathway. Repressor of HTR1A when nuclear. In the centrosome, regulates spindle pole localization of the cohesin subunit SCC1/RAD21, thereby mediating centriole cohesion during mitosis.
Protein Name	Coiled-Coil And C2 Domain-Containing Protein 1a Akt Kinase-Interacting Protein 1 Five Prime Repressor Element Under Dual Repression-Binding Protein 1 Fre Under Dual Repression-Binding Protein 1 Freud-1 Putative Nf-Kappa-B-Activating Protein 023n
Cellular Localisation	Cytoplasm Nucleus Cytoskeleton Microtubule Organizing Center Centrosome
Alternative Antibody Names	Anti-Coiled-Coil And C2 Domain-Containing Protein 1a antibody Anti-Akt Kinase-Interacting Protein 1 antibody Anti-Five Prime Repressor Element Under Dual Repression-Binding Protein 1 antibody Anti-Fre Under Dual Repression-Binding Protein 1 antibody Anti-Freud-1 antibody Anti-Putative Nf-Kappa-B-Activating Protein 023n antibody Anti-CC2D1A antibody Anti-AKI1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-CC2D1A antibody (STJ191919)