Human STAT5B (Signal Transducer And Activator Of Transcription 5B) Sandwich ELISA Kit Ready-To-Use (STJE0018756) STJE0018756 上海玉博生物科技有限公司

Human STAT5B (Signal Transducer And Activator Of Transcription 5B) Sandwich ELISA Kit Ready-To-Use (STJE0018756)

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产品名称：Human STAT5B (Signal Transducer And Activator Of Transcription 5B) Sandwich ELISA Kit Ready-To-Use (STJE0018756)
产品型号：STJE0018756
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human STAT5B (Signal Transducer And Activator Of Transcription 5B) Sandwich ELISA Kit Ready-To-Use (STJE0018756)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.137ng/mL
Detection Limit:	0.312-20ng/mL
Short Description:	This STAT5B Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	STAT5B
Gene ID:	6777
Uniprot ID:	STA5B_HUMAN
Immunogen Region:	Ready-To-Use
Sample Type:	tissue homogenates, cell lysates or other biological fluids.

Tissue Specificity
Post Translational Modifications	Tyrosine phosphorylated in response to signaling via activated KIT, resulting in translocation to the nucleus. Tyrosine phosphorylated in response to signaling via activated FLT3.wild-type FLT3 results in much weaker phosphorylation than constitutively activated mutant FLT3. Alternatively, can be phosphorylated by JAK2. Phosphorylation at Tyr-699 by PTK6 or HCK leads to an increase of its transcriptional activity.
Function	Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription. Positively regulates hematopoietic/erythroid differentiation.
Protein Name	Signal Transducer And Activator Of Transcription 5b
Database Links	Reactome: R-HSA-1170546 Reactome: R-HSA-1266695 Reactome: R-HSA-1433557 Reactome: R-HSA-1839117 Reactome: R-HSA-186763 Reactome: R-HSA-2586552 Reactome: R-HSA-512988 Reactome: R-HSA-8854691 Reactome: R-HSA-8983432 Reactome: R-HSA-8985947 Reactome: R-HSA-9020558 Reactome: R-HSA-9020958 Reactome: R-HSA-9027283 Reactome: R-HSA-9645135 Reactome: R-HSA-9670439 Reactome: R-HSA-9674555 Reactome: R-HSA-9702518 Reactome: R-HSA-9703465 Reactome: R-HSA-9705462 Reactome: R-HSA-982772
Cellular Localisation	Cytoplasm Nucleus Translocated Into The Nucleus In Response To Phosphorylation
Alternative ELISA Names	Signal Transducer And Activator Of Transcription 5b ELISA kit STAT5B ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Human STAT5B (Signal Transducer And Activator Of Transcription 5B) Sandwich ELISA Kit Ready-To-Use (STJE0018756)