Human SULF1 (Sulfatase 1) Sandwich ELISA Kit (STJE0012392) STJE0012392 上海玉博生物科技有限公司

Human SULF1 (Sulfatase 1) Sandwich ELISA Kit (STJE0012392)

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产品名称：Human SULF1 (Sulfatase 1) Sandwich ELISA Kit (STJE0012392)
产品型号：STJE0012392
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human SULF1 (Sulfatase 1) Sandwich ELISA Kit (STJE0012392)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.62ng/mL
Detection Limit:	1.56-100ng/mL
Short Description:	This SULF1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	SULF1
Gene ID:	23213
Uniprot ID:	SULF1_HUMAN
Sample Type:	serum, plasma, tissue homogenates or other biological fluids.

Tissue Specificity	Expressed at highest levels in testis, stomach, skeletal muscle, lung, kidney, pancreas, small intestine and colon. It is also detected in normal ovarian surface epithelial cells. Down-regulation seen in ovarian carcinoma cell lines, ovarian cancers, breast, pancreatic, renal and hepatocellular carcinoma cell lines.
Post Translational Modifications	Processing by furin produces a secreted form. The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.
Function	Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin. Diminishes HSPG (heparan sulfate proteoglycans) sulfation, inhibits signaling by heparin-dependent growth factors, diminishes proliferation, and facilitates apoptosis in response to exogenous stimulation.
Protein Name	Extracellular Sulfatase Sulf-1 Hsulf-1 Arylsulfatase N-Acetylglucosamine-6-Sulfatase Cleaved Into - Extracellular Sulfatase Sulf-2 Secreted Form
Database Links
Cellular Localisation	Endoplasmic Reticulum Golgi Apparatus Golgi Stack Cell Surface Extracellular Sulfatase Sulf-2 Secreted Form: Secreted
Alternative ELISA Names	Extracellular Sulfatase Sulf-1 ELISA kit Hsulf-1 ELISA kit Arylsulfatase ELISA kit N-Acetylglucosamine-6-Sulfatase Cleaved Into - Extracellular Sulfatase Sulf-2 Secreted Form ELISA kit SULF1 ELISA kit KIAA1077 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Human SULF1 (Sulfatase 1) Sandwich ELISA Kit (STJE0012392)