Anti-CLCN3 antibody (597-647 aa) (STJ195735) STJ195735 上海玉博生物科技有限公司

Anti-CLCN3 antibody (597-647 aa) (STJ195735)

简单介绍

Anti-CLCN3 antibody (597-647 aa) (STJ195735)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-H+/Cl-exchange transporter 3 (597-647 aa) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CLCN3
Gene ID:	1182
Uniprot ID:	CLCN3_HUMAN
Immunogen Region:	597-647 aa
Specificity:	This antibody detects endogenous levels of CLCN3 at Human/Mouse/Rat
Immunogen:	Synthesized peptide derived from the human CLCN3 at the amino acid range 597-647

Post Translational Modifications	N-glycosylated.
Function	Isoform 1: Strongly outwardly rectifying, electrogenic H(+)/Cl(-)exchanger which mediates the exchange of chloride ions against protons. The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons. The presence of conserved gating glutamate residues is typical for family members that function as antiporters. Isoform 2: Strongly outwardly rectifying, electrogenic H(+)/Cl(-)exchanger which mediates the exchange of chloride ions against protons.
Protein Name	H(+/Cl(- Exchange Transporter 3 Chloride Channel Protein 3 Clc-3 Chloride Transporter Clc-3
Database Links	Reactome: R-HSA-2672351
Cellular Localisation	Isoform 1: Early Endosome Membrane Multi-Pass Membrane Protein Late Endosome Membrane Lysosome Membrane Cell Membrane Isoform 1 Is Localized Mainly In Late Endosomes Isoform 2: Golgi Apparatus Membrane Cell Projection Ruffle Membrane Isoform 2 Is Mainly Enriched In The Golgi Colocalizes With Nherf1/Ebp50 In Membrane Ruffles
Alternative Antibody Names	Anti-H(+/Cl(- Exchange Transporter 3 antibody Anti-Chloride Channel Protein 3 antibody Anti-Clc-3 antibody Anti-Chloride Transporter Clc-3 antibody Anti-CLCN3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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