Anti-CLCN6 antibody (1-80) (STJ119574) STJ119574 上海玉博生物科技有限公司

Anti-CLCN6 antibody (1-80) (STJ119574)

简单介绍

Anti-CLCN6 antibody (1-80) (STJ119574)

产品描述

Host:	Rabbit
Applications:	IHC
Reactivity:	Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CLCN6 (1-80) is suitable for use in Immunohistochemistry research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	IHC 1:50-1:100
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CLCN6
Gene ID:	1185
Uniprot ID:	CLCN6_HUMAN
Immunogen Region:	1-80
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human CLCN6 (NP_001277.1).
Immunogen Sequence:	MAGCRGSLCCCCRWCCCCGE RETRTPEELTILGETQEEED EILPRKDYESLDYDRCINDP YLEVLETMDNKKGRRYEAVK

Tissue Specificity	Testis, ovary, small intestine, brain and skeletal muscle. Low level expression in aortic and coronary vascular smooth muscle cells, and aortic endothelial cells. Isoform 3 is only detected in kidney.
Post Translational Modifications	N-glycosylated on several asparagine residues.
Function	Voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the late endosome lumen. The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons. The presence of conserved gating glutamate residues is typical for family members that function as antiporters.
Protein Name	H(+/Cl(- Exchange Transporter 6 Chloride Channel Protein 6 Clc-6 Chloride Transport Protein 6
Database Links	Reactome: R-HSA-2672351 Reactome: R-HSA-6802952
Cellular Localisation	Late Endosome Membrane Multi-Pass Membrane Protein
Alternative Antibody Names	Anti-H(+/Cl(- Exchange Transporter 6 antibody Anti-Chloride Channel Protein 6 antibody Anti-Clc-6 antibody Anti-Chloride Transport Protein 6 antibody Anti-CLCN6 antibody Anti-KIAA0046 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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