Anti-CLDN16 antibody (50-150) (STJ111904) STJ111904 上海玉博生物科技有限公司

Anti-CLDN16 antibody (50-150) (STJ111904)

简单介绍

Anti-CLDN16 antibody (50-150) (STJ111904)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CLDN16 (50-150) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:100-1:500
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CLDN16
Gene ID:	10686
Uniprot ID:	CLD16_HUMAN
Immunogen Region:	50-150
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 50-150 of human CLDN16 (NP_006571.1).
Immunogen Sequence:	HLSGARAGVCPCCHPDGLLA TMRDLLQYIACFFAFFSAGF LIVATWTDCWMVNADDSLEV STKCRGLWWECVTNAFDGIR TCDEYDSILAEHPLKLVVTR A

Tissue Specificity	Kidney-specific, including the thick ascending limb of Henle (TAL).
Function	Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Involved in paracellular magnesium reabsorption. Required for a selective paracellular conductance. May form, alone or in partnership with other constituents, an intercellular pore permitting paracellular passage of magnesium and calcium ions down their electrochemical gradients. Alternatively, it could be a sensor of magnesium concentration that could alter paracellular permeability mediated by other factors.
Protein Name	Claudin-16 Paracellin-1 Pcln-1
Database Links	Reactome: R-HSA-420029
Cellular Localisation	Cell Junction Tight Junction Cell Membrane Multi-Pass Membrane Protein
Alternative Antibody Names	Anti-Claudin-16 antibody Anti-Paracellin-1 antibody Anti-Pcln-1 antibody Anti-CLDN16 antibody Anti-PCLN1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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