Human SUZ12 (Suppressor Of Zeste 12 Homolog) Sandwich ELISA Kit (STJE0012402) STJE0012402 上海玉博生物科技有限公司

Human SUZ12 (Suppressor Of Zeste 12 Homolog) Sandwich ELISA Kit (STJE0012402)

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产品名称：Human SUZ12 (Suppressor Of Zeste 12 Homolog) Sandwich ELISA Kit (STJE0012402)
产品型号：STJE0012402
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human SUZ12 (Suppressor Of Zeste 12 Homolog) Sandwich ELISA Kit (STJE0012402)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.113ng/mL
Detection Limit:	0.312-20ng/mL
Short Description:	This SUZ12 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	SUZ12
Gene ID:	23512
Uniprot ID:	SUZ12_HUMAN
Sample Type:	tissue homogenates or other biological fluids.

Tissue Specificity	Overexpressed in breast and colon cancer.
Post Translational Modifications	Sumoylated, probably by PIAS2.
Function	Polycomb group (PcG) protein. Component of the PRC2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.
Protein Name	Polycomb Protein Suz12 Chromatin Precipitated E2f Target 9 Protein Chet 9 Protein Joined To Jazf1 Protein Suppressor Of Zeste 12 Protein Homolog
Database Links	Reactome: R-HSA-212300 Reactome: R-HSA-2559580 Reactome: R-HSA-3214841 Reactome: R-HSA-4551638 Reactome: R-HSA-5617472 Reactome: R-HSA-8943724 Reactome: R-HSA-8953750 Reactome: R-HSA-9609690 Reactome: R-HSA-9710421
Cellular Localisation	Nucleus Localizes To Chromatin As Part Of The Prc2 Complex
Alternative ELISA Names	Polycomb Protein Suz12 ELISA kit Chromatin Precipitated E2f Target 9 Protein ELISA kit Chet 9 Protein ELISA kit Joined To Jazf1 Protein ELISA kit Suppressor Of Zeste 12 Protein Homolog ELISA kit SUZ12 ELISA kit CHET9 ELISA kit JJAZ1 ELISA kit KIAA0160 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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